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Biotech Ideas RSS Feed

Followers
16
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Posts (Total)
765
Created
04/23/20
Type
Free
Moderator gfp927z
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A board to discuss biotech ideas -


BioSpace - https://www.biospace.com/


BIG PHARMA -
******************


Abbott Labs (ABT) - Medical devices, diverse healthcare products (209 Bil) ----------------- 1.9%
AbbVie (ABBV) - Research unit from Abbott Labs (282 Bil) --------------------------------------- 4.0%   
Amgen (AMGN) - Biopharma (166 Bil) ------------------------------------------------------------------ 2.9  
AstraZeneca (AZN) - Pharmaceuticals (210 Bil) (UK) ----------------------------------------------- 2.1%   
Eli Lilly (LLY) - Pharmaceuticals (607 Bil) --------------------------------------------------------------- 0.8%
Johnson & Johnson (JNJ) - Diverse healthcare related products (389 Bil) (Berkshire) -- 2.9%   
Merck (MRK) - Pharmaceuticals (305 Bil) --------------------------------------------------------------- 2.6%   
Novartis (NVS) - Pharmaceuticals (209 Bil) ------------------------------------------------------------ 3.7%   
Novo Nordisk (NVO) - Pharmaceuticals (482 Bil) (Denmark) ------------------------------------- 1.0%
Pfizer (PFE) - Pharmaceuticals (160 Bil) ---------------------------------------------------------------- 5.9%   
Zoetis (ZTS) Veterinary drugs and vaccines (80 Bil) ------------------------------------------------- 0.7%



CROs -
**********


Icon PLC (ICLR) - CRO development svcs to biopharma ind (Ireland) (23 Bil) --------------- 0%
Medpace Holdings (MEDP) - CRO (10 Bil) ------------------------------------------------------------- 0%



BAKER BROS -   https://hedgefollow.com/funds/Baker+Bros+Advisors
*******************

Akero Therapeutics (AKRO) - Metabolic diseases -------------------------------------------- (BB) - (2 Bil)
Argenx SE (ARGX) - Autoimmune diseases (Netherlands) --------------------------------- (BB) - (32 Bil)

BeiGene (BGNE) - Oncology (Cayman Islands) ----------------------------------------------- (BB) - (20 Bil)
Bicycle Therapeutics (BCYC) - Oncology, other (UK) --------------------------------------- (BB) - (2 Bil)
Biocryst Pharma (BCRX) - Rare diseases ------------------------------------------------------ (BB) - (2 Bil)

Celcuity (CELC) - Oncology ------------------------------------------------------------------------- (BB) - (566 mil)
Celldex Therapeutics (CLDX) - Inflammatory, allergic, autoimmune diseases -------- (BB) - (2 Bil)
Denali Theapeutics (DNLI) - Neurodegenrative, lysosomal storage diseases --------- (BB) - (3 Bil)
Edgewise Therapeutics (EWTX) - Muscle disorders ----------------------------------------- (BB) - (1.5 Bil)
Entrada Therapeutics (TRDA) - Neuromuscular diseases ---------------------------------- (BB) - (473 mil)

Ideaya Biosciences (IDYA) - Oncology ----------------------------------------------------------- (BB) - (3 Bil)
Immatics (IMTX) - Oncology (Germany) --------------------------------------------------------- (BB) - (1 Bil)
Immunovant (IMVT) - Autoimmune diseases --------------------------------------------------- (BB) - (4 Bil)
Insmed (INSM) - Pulmonary, rare diseases ------------------------------------------------------ (BB) - (13 Bil)
Kiniksa Pharma Plc (KNSA) - Cardiovascular, other (UK) ---------------------------------- (BB) - (2 Bil)

Krystal Biotech (KRYS) - Rare diseases --------------------------------------------------------- (BB) - (5 Bil)
Madrigal Pharma (MDGL) - Liver, non-alcoholic steatohepatitis --------------------------- (BB) - (5 Bil)
Nurix (NRIX) - Oncology, inflammatory, other ---------------------------------------------------- (BB) - (1 Bil)
Revolution Medicines (RVMD) - Oncology ------------------------------------------------------ (BB) - (7 Bil)
Rhythm Pharma (RYTM) - Rare neuroendocrine diseases ---------------------------------- (BB) - (3 Bil)

Roivant Sciences Ltd (ROIV) - Inflammation, immunology (UK) -------------------------- (BB) - (8 Bil)
Sana Biotech (SANA) - Cell engineering platforms -------------------------------------------- (BB) - (1 Bil)
Sera Prognostics (SERA) - Women's health diagnostics, biomarker pregnancy tests (BB) - (241 mil)
Stoke Therapeutics (STOK) - Severe genetic diseases -------------------------------------- (BB) - (759 mil)
TScan Therapeutics (TCRX) - Oncology --------------------------------------------------------- (BB) - (312 mil)

Ultragenyx (RARE) - Rare and ultra-rare diseases -------------------------------------------- (BB) - (5 Bil)
Xenon Pharmaceuticals (XENE) - Neurological disorders (Canada) -------------------- (BB) - (3 Bil)



OTHER -
***********


Corcept Therapeutics (CORT) - Metabolic, oncology, neuropsych ------------------------------ (2.6 Bil)
Halozyme (HALO) - Drug delivery enhancement platform using hyaluronidase enzyme ----- (5 Bil)
Regeneron (REGN) - Eye, allerg, inflam, cardio, metab, infectious, cancer, pain, hematol - (106 Bil)
Vertex Pharmaceuticals (VRTX) - Cystic fibrosis, diabetes, other -------------------------------- (91 Bil) 
Viking Therapeutix (VKTX) - Metabolic and endocrine disorders ---------------------------------- (6 Bil)



MORE -
**********


Acurx (ACXP) - Antibiotics, C-Dif --------------------------------------------------------------------------- (30 mil)
Anavex (AVXL) - CNS disorders --------------------------------------------------------------------------- (535 mil)

Axsome Therapeutics (AXSM) - CNS disorders ------------------------------------------------------- (4 Bil)
Catalyst Pharma (CPRX) - Rare neuromuscular and neurological diseases -------------------- (2 Bil)
Novozymes (NVZMY) - Industrial enzymes, microorganisms, bio ingredients (Denmark) -- (29 Bil)
Simulations Plus (SLP) - Modeling + simulation software for drug development  0.6% ---- (737 mil)



Corvus Therapeutics (CRVS) - Immuno-oncology therapies ------------------------------- (B) -- (101 mil)
Dynavax (DVAX) - Vaccines, adjuvants ------------------------------------------------------------------ (1.5 Bil)
Enanta Pharma (ENTA) - Viral infections, liver diseases ------------------------------------- (D) -- (1.5 Bil)
Immutep Ltd (IMMP) - Cancer, autoimmune (Australia) ------------------------------------- (B) -- (310 mil)
Iovance (IOVA) - Cancer immunotherapy --------------------------------------------------------- (B) -- (4 Bil)
Jasper Therapeutics (JSPR) - Therapeutic agents for stem cell + gene therapies --- (B) -- (374 mil)
Kazia Therapeutics (KZIA) - Cancer (Australia) ----------------------------------------------- (B) - (112 mil)
Kura Oncology (KURA) - Cancer ------------------------------------------------------------------- (B) -- (2.2 Bil)



___________________________________________________________


ACQUIRED -
****************


Abgenix (ABGX) - Monoclonal antibodies (Amgen)
Actavis (ACT) - Generics, other (merged with Allergan)
Aduro Biotech (ADRO) - Immunotherapy, cancer, autoimmune (Chinook, 2020)
Allergan (AGN) -  Generic, branded, biosimilar, and OTC pharma products (Abbvie)

Ambrx BioPharma (AMAM) - Cancer, antibody-drug conjugates, genetic code platform (Amgen, 2024)
Arena Pharma (ARNA) - Immuno-inflammatory (Pfizer, 2021)
Ariad (ARIA) - Cancer (Takeda) 
Array (ARRY) - Cancer, inflammatory (Pfizer, 2019)
Bio-Reference Labs (BRLI) - Clinical laboratory testing services (Opko)
Celator (CPXX) - Cancer, dosage optimized liposome encapsulated combo drugs (Jazz)
Cambrex (CBM) - Active pharmaceutical ingredients and intermediates (Permira, 2019)
Celgene (CELG) - Cancer, inflam (Bristol-Myers Squibb)

Cerevel (CERE) - Neuroscience (Abbvie, 2023) (BB)
Cephalon (CEPH) - CNS (Teva) ------------------------------------------------------------------(Israel)

ChemoCentryx (CCXI) - Inflammatory, autoimmune, cancer (Amgen, 2022) (B)
Cubist (CBST) - Antibiotics (Merck)
Cynapsus (CYNA) - Oral rescue med for Parkinson's disease (Canada) (Sunovion)
Durata Therapeutics (DRTX) - Antibiotics (Actavis)

F-star Therapeutics (FSTX) - Tetravalent bispecific antibodies for cancer (UK) (InvoX Pharma, 2022) (B)

Genomic Health (GHDX) - Molecular diagnostics, genomic based lab tests (Exact Sciences, 2019)
Gentium (GENT) - Veno-occlusive disease (Italy) (Jazz)
Genzyme (GENZ) - Orphan diseases, other (Sanofi) --------------------------------------(France)
Given Imaging (GIVN) - Pill-Cam capsules for visualization of GI tract (Israel) (Covidien)

Gracell Biotechnologies (GRCL) - Cancer (China) (AstraZeneca, 2024) (B)
Idenix (IDIX) - Infectious diseases, Hep C (Merck)
Inhibitex (INHX) - Infectious diseases (BMY)
Kite Pharma (KITE) - Cancer (Gilead)
Life Technologies (LIFE) - Molecular biology related products (TMO)

Magenta Therapeutics (MGTA) - Autoimmune, MAB conjugates (Dianthus, 2023) (B)
Medarex (MEDX) - Monoclonal antibodies (BMY)
Medicines Co (MDCO) - Cardio, infectious, diseases (Novartis, 2019)
Medivation (MDVN) - Cancer, neurological (10.3 Bil) (Pfizer)
Momenta (MNTA) - Complex biosimilars, biogenerics (JNJ, 2020) (D)
Memory Pharma (MEMY) - CNS (Roche) ---------------------------------------------(Switzerland)
MGI Pharma (MOGN) - Oncology related (Eisai) -------------------------------------------(Japan)
Micromet (MITI) - Cancer (Amgen)
Millenium Pharma (MLNM) - Cancer (Takeda) ---------------------------------------------(Japan)
MWI Veterinary Supply (MWIV) - Veterinary drugs and products (Amerisource Bergen)

Myovant (MYOV) - Prostate cancer, women's health, endocrine diseases (UK) (Sumitoma)
Onyx (ONXX) - Cancer (Amgen)
Optimer - Antibiotics (Cubist) 
Pharmacyclics (PCYC) - Cancer, immune diseases (Abbvie)
Pharmasset (VRUS) - Infectious diseases (Gilead)
Polymedix (PYMX) - Defensin-mimetic antibiotics, other (Cellceutix)
Prolor (PBTH) - Long acting versions of therapeutic proteins (Opko)

Provention Bio (PRVB) - Immune-mediated diseases (2023, Sanofi) (B)
Salix (SLXP) - GI related disorders (Valeant)
Santarus (SNTS) - GI, diabetes, other (Salix)

Seagen (SGEN) - Cancer, autoimmune, armed MABs (Seattle Genetics) (Pfizer, 2023) (BB)
Senomyx (SNMX) - Taste modulators, flavor enhancing technology (Firmenich)
Shire (SHPG) - Pharmaceuticals (Takeda)
Sigma Aldrich (SIAL) - Bio research reagents, chemicals (Merck)
Synageva (GEVA) - Lysosomal storage disorders (Alexion)

Trillium Therapeutics (TRIL) - Immuno-oncology (Canada) (Pfizer)
Trius (TSRX) - Antibiotics (Cubist)
VCA Antech (WOOF) - Veterinary hospitals (Mars)
ViroPhama (VPHM) - Angioedema, infectious diseases, other (Shire) 



___________________________________________________________________

 

SPDR S&P Biotech ETF (XBI) (Exp - 0.35%, Assets - 3.5 Bil, Yld - 0.01%)

Name Symbol % Assets
Regeneron Pharmaceuticals Inc REGN 2.77%
Moderna Inc MRNA 2.65%
Gilead Sciences Inc GILD 2.43%
Vertex Pharmaceuticals Inc VRTX 2.32%
Biogen Inc BIIB 2.28%
United Therapeutics Corp UTHR 2.26%
Biomarin Pharmaceutical Inc BMRN 2.25%
Seattle Genetics Inc SGEN 2.16%
Exelixis Inc EXEL 2.06%
ACADIA Pharmaceuticals Inc ACAD 2.04%

__________________________________________________________________________

First Trust NYSE Arca Biotech Index (FBT) (Exp - 0.57%, Assets - 1.5 Bil, Yld - 0)

 

Name Symbol % Assets
Regeneron Pharmaceuticals Inc REGN 4.88%
Gilead Sciences Inc GILD 4.58%
Qiagen NV QGEN 4.48%
Biogen Inc BIIB 4.28%
Seattle Genetics Inc SGEN 4.08%
United Therapeutics Corp UTHR 3.93%
Vertex Pharmaceuticals Inc VRTX 3.89%
ACADIA Pharmaceuticals Inc ACAD 3.75%
Biomarin Pharmaceutical Inc BMRN 3.69%
Alnylam Pharmaceuticals Inc ALNY 3.53%

________________________________________________________________________
 

ARK Genomic Revolution ETF (ARKG) (Exp - 0.75%, Assets - 7.7 Bil, Yld - 0.85%)

 

Name Symbol % Assets
Pacific Biosciences of California Inc PACB 6.85%
Teladoc Health Inc TDOC 5.94%
CRISPR Therapeutics AG CRSP 5.77%
Twist Bioscience Corp TWST 5.72%
CareDx Inc CDNA 3.87%
Iovance Biotherapeutics Inc IOVA 3.59%
Exact Sciences Corp EXAS 3.58%
Fate Therapeutics Inc FATE 3.47%
Invitae Corp NVTA 3.42%
Personalis Inc PSNL 3.26%


_____________________________________________________________________________
 
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