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Bio-Path Holdings Inc. (BPTH)

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Last Post: 3/21/2019 9:15:30 PM - Followers: 128 - Board type: Free - Posts Today: 0





Bio-Path is engaged in the business of financing and commercializing novel cancer therapeutics acquired from MD Anderson Cancer Center. Their first Antisense drug BP-1001, known as Prexigebersen has completed a partial phase II combination trial (with LDAC). The interim results demonstrated 47% of the patients showed early anti-leukemic activity.


http://www.biopathholdings.com/wp-content/uploads/2018/04/BPTH_Interim_Phase_2_AML_Data_Release.pdf 

The Prexigebersen phase II trials for AML are located at MD Anderson, Weill Cornell Medical College Presbyterian Hospital, Baylor, New Jersey Hematology Oncology Associates, West Virginia University and University of Kansas.

Bio-Path Holdings is focused on antisense drugs which work at a cellular level to interrupt protein production by the diseased cell. The lead drug, Prexigebersen is targeting the Grb-2 protein. Bio Path Holdings' delivery system is a small molecule neutral liposome system. Through the phase 2 of the combination trial for Prexigebersen there has been absolutely no toxicity. The results of testing performed by Bio Path demonstrates an uptake of the drug at a cellular level. The pErk results demonstrate not only a 50+% knockdown of the target protein but shows the pathway was shut down validating the delivery system. The purpose of phase 2 will be to test the effectiveness of the drug. Interim results are positive.

A CML combination drug safety study with Sprycel (Dasatinib) for Prexigebersen has begun at MD Anderson.

Patent protection for manufacturing their neutral lipid delivery system has been granted.


http://www.biopathholdings.com

This link to the company website describes their delivery technology:


http://biopathholdings.com/technology/


The company was founded on the technology from M.D. Anderson Cancer Center at the University of Texas in Houston. M.D. Anderson is the largest insitutional shareholder. After raising additional funds the company has 2+ million in cash. BIO-PATH'S viability is in question due to a lack of funds.

 
Bio-Path Holdings does not manufacture their drugs but uses contractors, hence the need for partners.
 
BPTH is presently traded on the NASDAQ.

Here are links to articles on their drug technology:


http://www.abstractsonline.com/pp8/#!/4292/presentation/2610

http://www.biopathholdings.com/wp-content/uploads/2017/06/Published-Article-Evolution-of-Antisense-in-Oncology.pdf

http://www.biopathholdings.com/wp-content/uploads/2018/03/BPTH_Lancet_20180329.pdf


Stone Gate Capital "under valued"
https://finance.yahoo.com/news/stonegate-capital-partners-updates-coverage-213000664.html        
https://investorshub.advfn.com/75fb7cf5-a8b2-4eb3-b48e-3bb1403ff45a"="" rel="nofollow" target="_blank">; style="height:1.200000; width:234.840000">

Our press releases-See Links here
http://www.biopathholdings.com/press-release/


Bio-Path Holdings, Inc. Announces $18.5 Million Registered Direct Offering of Common Stock

 
 

 

 
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#5949   You will never know when the bottom will dinogreeves 03/21/19 09:15:30 PM
#5948   OSS will be the run tomorrow, dinogreeves 03/21/19 05:02:46 PM
#5947   Do yourselves all a favor and spend some iloveu2 03/21/19 03:51:47 PM
#5946   Bought some for a bounce slyguy8888 03/21/19 01:44:43 PM
#5945   sees you in and out down to 10 all right all right 03/21/19 01:18:36 PM
#5944   Just trading it...just took another .35 nice atm girlfriend 03/21/19 01:00:55 PM
#5943   Up $2.00 from its low. Maybe this NicksterPDX 03/21/19 12:56:39 PM
#5942   ride the wall of worry fear is not all right all right 03/21/19 12:52:57 PM
#5941   Nope...sold at 18.86 don't trust this much. girlfriend 03/21/19 12:43:00 PM
#5940   well i hope you get 27 today and all right all right 03/21/19 12:33:05 PM
#5939   19 now JohnnyVegas! I bought some at girlfriend 03/21/19 12:29:22 PM
#5938   ooppss it might be real he he all right all right 03/21/19 12:26:38 PM
#5937   so you didn't like 20 boy oh boy all right all right 03/21/19 12:06:09 PM
#5936   15.00's Here we come LOL ALL-IN888 03/21/19 12:03:14 PM
#5935   this is where it went 17--73 if it all right all right 03/21/19 12:03:01 PM
#5934   well well got to the 17esh he he all right all right 03/21/19 11:56:13 AM
#5933   He’s saying 15.80 ish now ..I just reloaded JohnnyVegas 03/21/19 11:48:23 AM
#5932   Expect BPTH to go much lower. Seen BRoberts1982 03/21/19 11:37:42 AM
#5931   I doubt it, Girlfriend. Lot of "talk" and NicksterPDX 03/21/19 11:28:47 AM
#5929   When Sabby decides they made enough money . too simple 03/21/19 11:18:52 AM
#5928   So we have moved below $20, Hope everyone Doc74 03/21/19 10:39:59 AM
#5927   Adding today! Bitcoins 03/21/19 12:03:15 AM
#5926   Backtested different timeframes on the lagging Indicators and ALL-IN888 03/20/19 10:09:54 PM
#5925   Gp, I got out of the majority of SJSTOCKSHARK 03/20/19 04:22:30 PM
#5924   Yes, ALL-IN888 is probably right about the price Gpheart2016 03/20/19 12:43:23 PM
#5923   Ok, I have to admit, you are calling Flops 03/20/19 12:33:43 PM
#5922   Well, I'm an original owner of 20,000 shares NicksterPDX 03/20/19 11:41:57 AM
#5921   no insider owns shares above 2 $ all right all right 03/20/19 11:19:58 AM
#5920   ohh you know it dilute dilute they all right all right 03/20/19 11:02:09 AM
#5919   NICK, We also raised 2.8 million in January. SJSTOCKSHARK 03/20/19 10:50:35 AM
#5918   do it all right all right 03/20/19 10:30:35 AM
#5917   Getting Closer & Closer to my Entry Point ALL-IN888 03/20/19 10:29:47 AM
#5916   Your marriage to bpth has been shared by dmoffat 03/20/19 10:27:03 AM
#5915   here is what happend to bpth that made all right all right 03/20/19 10:25:23 AM
#5914   2018 report was as expected. Now, $16 million NicksterPDX 03/20/19 10:05:30 AM
#5913   They just filed another offering. dinogreeves 03/19/19 08:30:07 PM
#5912   earning it was at one doller ps no all right all right 03/19/19 12:32:04 PM
#5911   lol bottom at 24 he he 22.5 by close all right all right 03/19/19 12:28:34 PM
#5910   yes GLTY ALL-IN888 03/19/19 12:27:02 PM
#5909   Are you jumping back in @ $20? Flops 03/19/19 12:22:05 PM
#5908   Bottomed $24+, run into earnings and conference time stockdawg44 03/19/19 10:58:12 AM
#5907   17 is the call and that all right all right 03/19/19 10:27:03 AM
#5906   I don't doubt your calls.....just the volume of girlfriend 03/19/19 10:16:59 AM
#5904   The PPS has moved straight down to the SJSTOCKSHARK 03/19/19 10:07:32 AM
#5903   See ya @ 20.00 Promise!!! :-D ALL-IN888 03/19/19 10:03:24 AM
#5902   25.15 LOL ALL-IN888 03/19/19 09:59:26 AM
#5901   Thank you.....for not posting as often recently. girlfriend 03/19/19 09:58:37 AM
#5900   The impression it gave me was that they dmoffat 03/19/19 09:19:06 AM
#5899   WOW! Did somebody fart? Everyone's left the room! NicksterPDX 03/19/19 08:56:24 AM
#5898   The Reg. D filing is required for unregistered wordlender 03/19/19 07:50:07 AM
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