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Bio-Path Holdings Inc. (BPTH)

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Last Post: 4/1/2020 11:50:15 AM - Followers: 113 - Board type: Free - Posts Today: 0

Bio-Path is engaged in the business of financing and commercializing novel cancer therapeutics acquired from MD Anderson Cancer Center. Their first Antisense drug BP-1001, known as Prexigebersen has completed a partial phase II combination trial (with LDAC). The interim results demonstrated 47% of the patients showed early anti-leukemic activity.


The Prexigebersen phase II trials for AML are located at MD Anderson, Weill Cornell Medical College Presbyterian Hospital, Baylor, New Jersey Hematology Oncology Associates, West Virginia University and University of Kansas.

Bio-Path Holdings is focused on antisense drugs which work at a cellular level to interrupt protein production by the diseased cell. The lead drug, Prexigebersen is targeting the Grb-2 protein. Bio Path Holdings' delivery system is a small molecule neutral liposome system. Through the phase 2 of the combination trial for Prexigebersen there has been absolutely no toxicity. The results of testing performed by Bio Path demonstrates an uptake of the drug at a cellular level. The pErk results demonstrate not only a 50+% knockdown of the target protein but shows the pathway was shut down validating the delivery system. The purpose of phase 2 will be to test the effectiveness of the drug. Interim results are positive.

A CML combination drug safety study with Sprycel (Dasatinib) for Prexigebersen has begun at MD Anderson.

Patent protection for manufacturing their neutral lipid delivery system has been granted.


This link to the company website describes their delivery technology:


The company was founded on the technology from M.D. Anderson Cancer Center at the University of Texas in Houston. M.D. Anderson is the largest insitutional shareholder. After raising additional funds the company has 2+ million in cash. BIO-PATH'S viability is in question due to a lack of funds.

Bio-Path Holdings does not manufacture their drugs but uses contractors, hence the need for partners.
BPTH is presently traded on the NASDAQ.

Here are links to articles on their drug technology:




Stone Gate Capital "under valued"
https://investorshub.advfn.com/75fb7cf5-a8b2-4eb3-b48e-3bb1403ff45a"="" rel="nofollow" target="_blank">; style="height:1.200000; width:234.840000">

Our press releases-See Links here

Bio-Path Holdings, Inc. Announces $18.5 Million Registered Direct Offering of Common Stock



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#6270   Your think that does not happen more often Doc74 04/01/20 11:50:15 AM
#6269   Would that not be insider trading? SJSTOCKSHARK 03/27/20 04:39:01 PM
#6268   That is likely true AND the fact that Runninonempty 03/27/20 11:54:26 AM
#6267   Why the jump in PPS today? It must SJSTOCKSHARK 03/27/20 11:34:27 AM
#6266   No nibbling here! I have sold ALL my SJSTOCKSHARK 03/18/20 03:25:15 PM
#6265   I smell a reverse stock split coming slapshot120 03/17/20 11:17:33 AM
#6264   no worries pete doesn't play golf.if he did slapshot120 03/17/20 11:12:49 AM
#6263   Not me ! I am nibbling at others too simple 03/17/20 09:30:35 AM
#6262   I have such a toxic relationship with this Billlowenswartz 03/14/20 08:28:19 PM
#6261   I have such a toxic relationship with this Billlowenswartz 03/14/20 08:27:27 PM
#6260   Runin, I seems to me PN is most SJSTOCKSHARK 03/07/20 11:11:09 AM
#6259   I have been listening to PN’s conference calls Runninonempty 03/06/20 09:18:50 AM
#6258   Results are out. Only $20 million left. Two SJSTOCKSHARK 03/06/20 09:17:41 AM
#6257   The chart looks a whole lot different a nsomniyak 03/03/20 07:23:36 PM
#6256   Dead cat bounce, anniversary of huge move, test Runninonempty 03/03/20 05:16:06 PM
#6255   So why the big move today, not seeing Doc74 03/03/20 04:25:48 PM
#6254   https://www.youtube.com/watch?v=JCpnk5OuzUE blairsoldman 02/27/20 02:52:56 PM
#6253   Another buck to downside and I may start SJSTOCKSHARK 02/26/20 09:05:21 PM
#6252   More sellers of BPTH. SJSTOCKSHARK 02/14/20 07:32:24 PM
#6251   No, I meant from the BOD position. Perhaps SJSTOCKSHARK 02/13/20 12:22:01 PM
#6250   SJ I saw your post on Stocktwits and below. Billlowenswartz 02/13/20 12:56:48 AM
#6249   Up to $4 million for PN and more SJSTOCKSHARK 02/12/20 11:46:09 PM
#6248   SJ, your a smart man. I also sold too simple 02/06/20 09:34:20 PM
#6247   They need to keep at least a million SJSTOCKSHARK 02/06/20 02:35:30 PM
#6246   You still believe!! blairsoldman 02/06/20 12:42:14 PM
#6245   Oldman, This may be a buy if we SJSTOCKSHARK 02/05/20 11:30:23 PM
#6244   It is becoming harder and harder to avoid blairsoldman 02/05/20 10:43:10 PM
#6243   why are there only 2 post in the slapshot120 02/05/20 02:51:56 PM
#6242   As an old investor (both by age and blairsoldman 02/02/20 05:23:27 PM
#6241   don'tyou find it interesting that BOD has lost slapshot120 01/13/20 03:50:58 PM
#6240   My hope is PN realizing he is not Runninonempty 01/08/20 02:22:46 PM
#6239   My hope is PN realizing he is not Runninonempty 01/08/20 02:22:45 PM
#6238   Folks we are still years away from FDA approval. SJSTOCKSHARK 01/08/20 12:40:50 PM
#6237   Bio-Path Holdings Provides Clinical Update and 2020 Business Outlook Paullee 01/08/20 08:20:20 AM
#6236   The FDA approves a new drug for pancreatic SJSTOCKSHARK 12/31/19 11:58:02 AM
#6235   One thing is certain. PN certainly makes sure SJSTOCKSHARK 12/24/19 11:25:15 AM
#6234   The fox is in the hen house again. SJSTOCKSHARK 12/24/19 11:22:36 AM
#6233   HC Wainwright had it at 28.00, but then NicksterPDX 12/23/19 02:00:08 PM
#6232   who has the 28 target ? Paullee 12/18/19 03:01:07 PM
#6231   With all these analyst's upgrades, why is this NicksterPDX 12/18/19 11:10:00 AM
#6230   Trial listed SJSTOCKSHARK 12/15/19 09:06:57 PM
#6229   BPTH volume in trading and stocktwits posts both SJSTOCKSHARK 12/06/19 12:22:05 PM
#6228   Paullee - thanks for the info. Doc74 12/06/19 11:01:45 AM
#6227   Stonegate Capital Partners Updates Coverage on Bio-Path Holdings, Inc. Paullee 12/06/19 09:36:42 AM
#6226   Our market cap now equals cash on hand. SJSTOCKSHARK 12/05/19 01:01:01 PM
#6225   From Fidelity, yes thing are looking up for Doc74 12/05/19 11:02:44 AM
#6224   Looks good europtiger 12/05/19 08:50:35 AM
#6223   Don’t know... I just buy the breakout europtiger 12/04/19 02:52:18 PM
#6222   Why the big move? No news that I see. Doc74 12/04/19 02:27:49 PM
#6221   And going europtiger 12/04/19 02:11:07 PM