Anavex Life Sciences Corp (AVXL)

[Anshu2]

Haha. Fools are easily fooled. It takes 2+ months to calculate basic measures??!! No — it’s a few hours job, at most!

[oldandintheway]

and just like that the buying pressure evaporates, instantly. Amazing.

[boi568]

I think there are large gaps between test completion and full readout because Anavex is both conducting clinical trials and wide-ranging, groundbreaking scientific research.

Anavex is the first to seriously explore the Sigma 1 receptor and its effect on CNS disease at large. This is a much more ambitious undertaking than just going through one monoclonal antibody after another, like Edison searching for the best light bulb filament. It goes quicker if you take the time to get it right the first time. And the payoff, as Missling has suggested over the years, will be worth the wait.

[Kb1123]

Spoke to soon

[WolfofMia]

Lmao oh no my feelings are going to get hurt if you dont!

Are you sure you dont want to and arent going to?

[WolfofMia]

Another enthusiastic share holder lol

What a joke!

[Bourbon_on_my_cornflakes]

if all fails the next step is to put Blacamesine for sale as a dietary supplement, which the FDA doesn't regulate

Nope. 273 cannot be sold as a supplement, as it doesn't derive from natural sources, it is a lab developed chemical.

That is how the dem FDA destroyed Rock Creek Pharma, which was linked to a GOP governor of Virginia, even though Anatabloc is derived from Tobacco.

Thankfully you can purchase in the UK for about $1.20 per daily dose.

[abew4me]

No. The XBI has just turned down sharply...and has taken all of the biotechs down with it.

Thankfully, we're still way ahead.

[Hoskuld]

The call was short and sweet. The company y reiterated that they are succeeding and they ended the call. They are focused on execution and there is no need to gild the lily.

[Bourbon_on_my_cornflakes]

Missling's INaction. A conference call full of mananas.

Everything promised for last year will maybe get started this year. Maybe.

So of course the stock is up. go figure.

I understood the need for a large data analysis time for PD, which was a fishing trip.

But to take forever with alz, which was a targeted test, seems strange. Only AVXL has these enormous gaps between test completion and data presentation.'

[mrplmer]

pump and dump

[longtermbeliever]

what if DR.M release a full DATA result tomorrow hummm.JUST HOLD ON TIGHT LOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOONGS

[bas2020]

LOL!!!

[Anshu2]

BUT, I don't trust CM anymore. He is a liar/truth-hider. So will sell 50% of my position over the short term, and keep the rest as a lottery ticket (anything is still possible with AVXL -- except the time frame can be as long as 5-7 years).

[Anshu2]

IMO, the stock is worth $12-24, even if the P2b/3 is a NON-pivotal trial. Each CC/event only makes the stock move forward (confirmation of what is to come -- Rett P3 results, full AD results, etc. etc).

That's my thinking and rationale to the stock's movement.

[gbrown6332]

nidan7500... In spite of my misgivings the market has responded really well to the call.

[Joseph_K]

Did Missling utter some secret code word?

There was nothing I noticed in the call that would have surprised anybody or, long or short, impacted their convictions. But the share price is acting like he did.

[sab63090]

I promise I'm gonna shut up after this!

If we are able to surpass 13.50, I will be forced to review my upside target substantially!

Damn, I better clamp up now.....lol

[LBSR TO DA MOON]

AVXL is up nearly 50% over the past 2 months. If it can somehow continue this trend until June 2024, AVXL will be around $300 per share at that time. About 75% lower than your prediction, but I sure as heck would take it in a heartbeat!

Consensus is $1249 AVXL stock price by June 2024!!

[sab63090]

Kund

Here's Missling's reply:

"But obviously, we will catch up very nicely now with all these trials, which we plan to do. And they are still on track to be executed"

You seem to like to read the questions, but don't consider the replies

[crescentmotor]

The trend is your friend. And the trend is definitely moving higher...on really good volume, too!

Rett juvenile results are a relatively near-term event and that will work in our favor.

[BIOChecker4]

“Consensus is $1249 AVXL stock price by June 2024!!”

A consensus of 1 is an oxymoron.

[abew4me]

Agreed. Looking forward to $12/share today.

Someone pass the popcorn!

[LBSR TO DA MOON]

Soumit Roy of Jones Trading seems pleased with the CC. Heck, maybe he will raise his PT up into three-digit land!

[bas2020]

...and could substantially accelerate once the XBI turns.

[sab63090]

A refreshing change of trading:

We held that 11 pullback (plus or minus) and have been able to take out the 3 day chop which was a bit frustrating to me!

The 13 spike high back in December stands out as a fairly reasonable short term target for now.

[abew4me]

Even more important is that it's going higher even after Dr. M spoke. LOL

This too must put a smile on Mike.com's face.

[LBSR TO DA MOON]

Geez EBZ, I can't believe that's your response to my post. Did I really need to include a "sarc" flag? Wow...

Eps on a prerevenue stock mean absolutely nothing

[georgejjl]

AVXL could trade over 2 million shares by or before the close of trading today Tuesday 7 February 2023.

Good luck and GOD bless,

[abew4me]

Yup. The trend is your friend. And the trend is definitely moving higher...on really good volume, too!

This must put a smile on SAB's face because this is the type of action he wanted to see to confirm a major turning point.

[longtermbeliever]

not looking good for shorty from this point on i believe will may see some fireworks soon.JUST HOLD ON TIGHT LOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOONGS

[georgejjl]

This is NOT a new endpoint for the EXCELLENCE trial. This is the same endpoint as the AVATAR trial.

Stop the spin on this discussion board.

Primary Outcome Measures :
RSBQ [ Time Frame: 12 weeks ]
Change from baseline to End of Treatment (EOT) in the Rett Syndrome Behaviour Questionnaire (RSBQ) Total score

Incidents of Adverse Events [ Time Frame: 12 weeks ]
Change from baseline to End of Treatment (EOT)

https://clinicaltrials.gov/ct2/show/NCT04304482

***********************************************************************************************************

Primary Outcome Measures :
RSBQ [ Time Frame: 7 weeks ]
Drug exposure-dependent response of the Rett Syndrome Behaviour Questionnaire (RSBQ) Total score

Incidence of Adverse Events [ Time Frame: 7 weeks ]
Incidence of Adverse Events

https://clinicaltrials.gov/ct2/show/NCT03941444

Good luck and GOD bless,

[sab63090]

Leo: When is bad news, good news?

This takes me back quite a few years & as best as I can recall:

A company named Sandisk and Lexar were "in battle" over the best SD cards and Lexar was considered superior to Sandisk's by professional photo guys, but were losing the battle. over poorly run CEO over at Lexar....they reported lousy results and low and behold Carl Icahn took a nice position in Lexar, that day; I bought in!

As I recall it was around $5 per share and the stock "took off"....so, I would think you know that Carl Icahn is one sharp cookie...I made a sizable profit.

:)

[bas2020]

Ha. I think investors know very well that Anavex will use the measurement that the FDA wants to see.

[WolfofMia]

Hey Doc are you getting wrecked by todays price action?

Or are you long again?

[boi568]

Imagine how much higher the price would be today if Missling were going to use RSBQ-AUC in EXCELLENCE!

[longtermbeliever]

feel like SP going to explode soon..18M SHORTY NEEDED TO COVER.JUST HOLD ON TIGHT LOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOONGS

[longtermbeliever]

every sell order today got bought quickly very nice.JUST HOLD ON TIGHT LOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOONGS

[Simonizer]

Very impressive trading day so far. Up over 5% on volume over 750k. The other bios SAVA XBI ANVS and BIIB all down between 1/2 and 5%.

[JWC3]

Consensus is $1249 AVXL stock price by June 2024!!

[bas2020]

LOL!!! Did you notice the rising price today? Seems investors are expecting commercialization this year... and shorts are covering.

[kund]

Remove your rose colored glasses, my track record; 100% correct since 2015.

[georgejjl]

Expect FDA approval before the end of 2023.

Good luck and GOD bless,

[Anshu2]

I’ll be “ok” (accepting the fate) if they all just fail. But very furious if CM puts out a new-endpoint and spins it. Why furious? Well, difficult to pin point …

[plexrec]

Question--do tutes--the big guys have more information (re: co.) than the average retail investor ??? Can they (do they) get deeper (closer to the co.) info than is available to john Q public ?? (like private personal phone calls to insiders-people in the know ????) Just curious !!!!

[plexrec]

"Nice price action today."-yes and with decent volume--good to see--buyers stepping up !!

[kund]

AVXL2-73 will not see light in the market, this company will be wrapped up once AD full data is released in 2025 like CRTX

[jbcan07]

One does not need to be in the WGT camp to suggest a small change to the AI-generated text to this... "but it will require further clinical trial results to determine..." rather than "but it will require further clinical trials to determine..."

The fact is the current trial results are pending and it is not impossible that those results, fully revealed, may validate 2-73 efficacy.

Now you may as a investor/trader/speculator judge, based on the available facts, experience and intuition, that it is very likely to require actual further trials to find demonstrable truths.

[raja48185]

Then life goes on for me.

What about you ?

[Gator328]

As I've said before, if all fails the next step is to put Blacamesine for sale as a dietary supplement, which the FDA doesn't regulate. Make billions following the Herbalife model.

Or move on and spend the $140 million advancing A371 or developing new drugs for the pipeline and focus on Rett, where approval is much more likely given the adult results and lack of alternative treatments.