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Anavex Life Sciences Corp (AVXL)

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Last Post: 12/14/2017 4:06:20 PM - Followers: 718 - Board type: Free - Posts Today: 104

Anavex Life Sciences Corp (AVXL)

Company website:
Company Address:
51 West 52nd Street, 7th floor
New York, NY
10019 USA

CIK:  0001314052

Anavex®Life Sciences Corp. (the “Company”) is a clinical stage biopharmaceutical company engaged in the development of differentiated therapeutics for the treatment of neurodegenerative and neurodevelopmental diseases including drug candidates to treat Alzheimer’s disease, other central nervous system (“CNS”) diseases, pain and various types of cancer.  The Company’s lead compound ANAVEX®2-73 is being developed to treat Alzheimer’s disease, Parkinson’s disease and potentially other central nervous system diseases, including rare diseases, such as Rett syndrome.

Anavex®Life Sciences’ lead drug candidate, ANAVEX®2-73, recently completed successfully a Phase 2a clinical trial for Alzheimer’s disease.  ANAVEX®2-73 is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors.  Preclinical studies demonstrated its potential to halt and/or reverse the course of Alzheimer’s disease. It has also exhibited anticonvulsant, anti-amnesic, neuroprotective and anti-depressant properties in animal models, indicating its potential to treat additional CNS disorders, including epilepsy and others.  The Michael J. Fox Foundation for Parkinson’s Research has awarded Anavex® a research grant to develop ANAVEX®2-73 for the treatment of Parkinson’s disease to fully fund a preclinical study, which could justify moving ANAVEX®2-73 into a Parkinson’s disease clinical trial.  ANAVEX®3-71, also targeting sigma-1 and M1 muscarinic receptors, is a promising preclinical drug candidate demonstrating disease modifications against the major Alzheimer’s hallmarks in transgenic (3xTg-AD) mice, including cognitive deficits, amyloid and tau pathologies, and also with beneficial effects on neuroinflammation and mitochondrial dysfunctions.

The Company is in preparation for ANAVEX®2-73 for a Phase 2/3, placebo-controlled trial in Alzheimer’s disease as well as a Phase 2, placebo-controlled trial in Rett syndrome, for which the U.S. Food and Drug Administration (FDA) granted Orphan Drug Designation (ODD) for ANAVEX®2-73 and a Phase 2, placebo-controlled trial in Parkinson’s disease.

Headquartered in New York, Anavex® Life Sciences is an American publicly traded corporation on Nasdaq quoted as AVXL


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Clinical Trials:
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AVXL News: Annual Report (10-k) 12/11/2017 05:17:35 PM
AVXL News: Anavex Life Sciences Reports Fiscal 2017 Financial Results And Provides Update On Therapeutic Programs 12/11/2017 07:00:00 AM
AVXL News: Anavex Life Sciences Reports Newly Published Data on Alzheimer's Disease Research Demonstrate the Neuroprotective Features of... 11/21/2017 07:00:00 AM
AVXL News: Anavex Life Sciences to Present at the 5th Annual Mental Health Parity Addiction Equity Act Business Roundtable in Washington... 11/08/2017 07:00:00 AM
AVXL News: Anavex Life Sciences Presents New Clinical Data of Investigational Alzheimer’s Disease Treatment ANAVEX®2-73 at 2017 Clini... 11/04/2017 03:30:00 PM
#133249  Sticky Note Fact: the company continues to use unambiguous polarbear77 12/07/17 12:00:43 PM
#131122  Sticky Note Has Anavex progressed too slowly and not kept Investor2014 11/20/17 07:44:47 AM
#129044  Sticky Note People seem to always lose track of the dadofmarcmax 11/06/17 10:58:33 AM
#116985  Sticky Note Anavex Life Sciences Corp. - Things To Know. nobrainerstocks 08/24/17 06:32:49 AM
#103034  Sticky Note To answer your good questions. falconer66a 04/26/17 10:18:09 AM
#134377   No Really..MAXIM Grp rates AVXL buy...$14.00...we'll take 4 nidan7500 12/14/17 04:06:20 PM
#134376   If you look at 3.2 You just might find Cbdpotential 12/14/17 03:58:50 PM
#134375   Trial start date drama is pure FUD imo Cbdpotential 12/14/17 03:56:00 PM
#134374   I gotta admit, the year long chart is djmurdock 12/14/17 03:51:40 PM
#134373   Thank you Mycroft for your input it's really anders2211 12/14/17 03:49:01 PM
#134372   if it was due to FDA promise, M samk 12/14/17 03:33:45 PM
#134371   Price action today.... 123tom 12/14/17 03:25:45 PM
#134370   Australia won't start until the U.S. does because XenaLives 12/14/17 03:19:01 PM
#134369   Re: Anavex- The Road Forward MycroftHolmes 12/14/17 03:18:02 PM
#134368   I agree, Anavex will have to adapt to basparks79 12/14/17 03:04:51 PM
#134367   Rett in the US- with their funding Jonjones325 12/14/17 03:03:46 PM
#134366   There’s no doubt that our Alz trial delay Jonjones325 12/14/17 02:58:22 PM
#134365   if anavex will stumble and fumble or nor anders2211 12/14/17 02:33:23 PM
#134364   well said Attila. anders2211 12/14/17 02:31:10 PM
#134362   Saw polar's comment and removed mine. powerwalker 12/14/17 01:48:30 PM
#134360   ok thanks attila anders2211 12/14/17 01:33:28 PM
#134359   European regulatory authorities could be the countries too, anders2211 12/14/17 01:32:58 PM
#134358   Thank you. baltimorebullet 12/14/17 01:31:35 PM
#134357   Maybe the answer is easier. The Rhett monarch6500 12/14/17 01:28:06 PM
#134356   I'd speculate that Missling may not be solely sumbuysumsell 12/14/17 01:18:02 PM
#134354   My 2 cents on PD: I respect your opinion polarbear77 12/14/17 12:55:59 PM
#134353   It's effecting your Buzz mrplmer 12/14/17 12:32:33 PM
#134352   Thanks. Here’s another link. Which says. Jonjones325 12/14/17 12:28:58 PM
#134351   You're right but what I think will happen attilathehunt 12/14/17 12:27:42 PM
#134350   Thank you, that was an important clarificaton. XenaLives 12/14/17 12:25:47 PM
#134349   If it is registered through a country it XenaLives 12/14/17 12:23:58 PM
#134348   Partnership news with Biogen could come at any Turner2017 12/14/17 12:21:16 PM
#134347   Anders - Don't waste your time. Anavex attilathehunt 12/14/17 12:21:11 PM
#134346   My reading(bias) on what M. says has just nidan7500 12/14/17 12:20:01 PM
#134345   That could very well be. The challenge attilathehunt 12/14/17 12:16:56 PM
#134344   Quick clarification re Dr M’s answer regarding MS polarbear77 12/14/17 12:13:05 PM
#134343   BB - We are moving forward with that attilathehunt 12/14/17 12:10:34 PM
#134342   Sound advice Investor. attilathehunt 12/14/17 12:06:22 PM
#134341   MMMM You know what Im going to give anders2211 12/14/17 12:02:15 PM
#134340   Indeed. I feel the need to assist F1ash Investor2014 12/14/17 11:59:07 AM
#134339   PD in the EU may have come from sumbuysumsell 12/14/17 11:57:51 AM
#134338   I don't believe Missling has a deceitful bone basparks79 12/14/17 11:57:38 AM
#134336   Any thoughts what he meant here timelinewise in baltimorebullet 12/14/17 11:54:27 AM
#134335   It seems that there is a delay there XenaLives 12/14/17 11:54:20 AM
#134334   I have said before, but not all agree, Investor2014 12/14/17 11:53:21 AM
#134333   Christopher Missling baltimorebullet 12/14/17 11:51:10 AM
#134332   I could not find any fillings for Anavex anders2211 12/14/17 11:47:41 AM
#134331   JJ?? The newly formed ACTC may be involved in nidan7500 12/14/17 11:44:53 AM
#134330   Is "This will be now a European trial" baltimorebullet 12/14/17 11:40:05 AM
#134329   Investor...Yes, Caroline also seemed surprised PD was moving attilathehunt 12/14/17 11:37:15 AM
#134328   Indeed, so not too bad! Investor2014 12/14/17 11:32:01 AM
#134327   Agreed whippinsaw re MS, when will we finally polarbear77 12/14/17 11:31:53 AM
#134326   I've sat through some investments that stumbled and baltimorebullet 12/14/17 11:29:33 AM
#134325   LET me explain in a way you might attilathehunt 12/14/17 11:28:06 AM
#134324   Jon -An excerpt from NIH news release posted drv17 12/14/17 11:24:48 AM