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Anavex Life Sciences Corp (AVXL)

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Last Post: 3/20/2019 8:29:32 PM - Followers: 734 - Board type: Free - Posts Today: 109

Anavex Life Sciences Corp (AVXL)

Company website:  http://www.anavex.com/
Company Address:
51 West 52nd Street, 7th floor
New York, NY
10019 USA

CIK:  0001314052

Anavex®Life Sciences Corp. (the “Company”) is a clinical stage biopharmaceutical company engaged in the development of differentiated therapeutics for the treatment of neurodegenerative and neurodevelopmental diseases including drug candidates to treat Alzheimer’s disease, other central nervous system (“CNS”) diseases, pain and various types of cancer.  The Company’s lead compound ANAVEX®2-73 is being developed to treat Alzheimer’s disease, Parkinson’s disease and potentially other central nervous system diseases, including rare diseases, such as Rett syndrome.

Anavex®Life Sciences’ lead drug candidate, ANAVEX®2-73, recently completed successfully a Phase 2a clinical trial for Alzheimer’s disease.  ANAVEX®2-73 is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors.  Preclinical studies demonstrated its potential to halt and/or reverse the course of Alzheimer’s disease. It has also exhibited anticonvulsant, anti-amnesic, neuroprotective and anti-depressant properties in animal models, indicating its potential to treat additional CNS disorders, including epilepsy and others.  The Michael J. Fox Foundation for Parkinson’s Research has awarded Anavex® a research grant to develop ANAVEX®2-73 for the treatment of Parkinson’s disease to fully fund a preclinical study, which could justify moving ANAVEX®2-73 into a Parkinson’s disease clinical trial.  ANAVEX®3-71, also targeting sigma-1 and M1 muscarinic receptors, is a promising preclinical drug candidate demonstrating disease modifications against the major Alzheimer’s hallmarks in transgenic (3xTg-AD) mice, including cognitive deficits, amyloid and tau pathologies, and also with beneficial effects on neuroinflammation and mitochondrial dysfunctions.

The Company is in preparation for ANAVEX®2-73 for a Phase 2/3, placebo-controlled trial in Alzheimer’s disease as well as a Phase 2, placebo-controlled trial in Rett syndrome, for which the U.S. Food and Drug Administration (FDA) granted Orphan Drug Designation (ODD) for ANAVEX®2-73 and a Phase 2, placebo-controlled trial in Parkinson’s disease.

Headquartered in New York, Anavex® Life Sciences is an American publicly traded corporation on Nasdaq quoted as AVXL

Management:   http://www.anavex.com/about-us/leadership/
Pipeline:  http://www.anavex.com/pipeline/

Patent Info: 

Clinical Trials:  https://clinicaltrials.gov/ct2/results?term=Anavex+Life+Sciences&Search=Search
Recent News:  http://finance.yahoo.com/q?s=avxl&ql=1
Company News Releases:  http://www.anavex.com/2015/?post_type=news
Filings:  http://www.sec.gov/cgi-bin/browse-edgar?company=anavex&owner=exclude&action=getcompany
Share Structure:  See SEC filings
Investor Relations:  ir@anavex.com

Marketing Details:  http://convention.bio.org/Printables/Anavex%20Life%20Sciences%20Corp..html


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AVXL News: Industry Consortium Launched to Qualify Biomarkers for Schizophrenia Drug Development 09:00 AM
AVXL News: Anavex Life Sciences Announces First Patient Dosed in Phase 2 Clinical Trial of ANAVEX®2-73 for the Treatment of Rett Syndro... 03/18/2019 07:00:00 AM
AVXL News: Current Report Filing (8-k) 03/18/2019 06:28:15 AM
AVXL News: Prospectus Filed Pursuant to Rule 424(b)(5) (424b5) 03/18/2019 06:13:43 AM
AVXL News: Anavex Life Sciences to Present at the 31st Annual ROTH Conference 2019 03/13/2019 07:00:00 AM
News News Alert: Industry Consortium Launched to Qualify Biomarkers for Schizophrenia Drug Development 03/20/2019 09:00:00 AM
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#185524  Sticky Note Compiled Due Diligence 03/17/19 XenaLives 03/17/19 12:24:18 PM
#166633  Sticky Note Thanks T... More to your post neiu 09/25/18 07:28:46 AM
#160507  Sticky Note here are a couple of those 32 from cninc 07/30/18 12:01:12 AM
#135567  Sticky Note Good lessons learned from AVXL investment in 2017. Rising_Sun 12/29/17 02:53:39 AM
#129044  Sticky Note People seem to always lose track of the dadofmarcmax 11/06/17 10:58:33 AM
#185966   Sounds familiar! I hope we hear it bennyboy1 03/20/19 08:29:32 PM
#185965   George - Doctors asking patients to get in bennyboy1 03/20/19 08:23:36 PM
#185964   The bain in Spain falls mainly on the brain indialong 03/20/19 07:56:48 PM
#185963   Involvement of Striatal Cholinergic Interneurons and M1 and georgejjl 03/20/19 07:44:25 PM
#185962   Of course we all know that Anavex 2-73 georgejjl 03/20/19 07:28:35 PM
#185961   nidan7500, I agree 100% georgejjl 03/20/19 07:20:17 PM
#185960   georgejjl, I think it’s good the Doctors are actively tradeherpete 03/20/19 07:11:02 PM
#185959   sounds logical !!!! georgejjl 03/20/19 07:10:12 PM
#185958   george-" that so many doctors in Spain"--could be plexrec 03/20/19 07:06:56 PM
#185957   Question for everyone!!! georgejjl 03/20/19 06:57:18 PM
#185956   Thanks VG. I don't think they have pcguy 03/20/19 06:43:14 PM
#185955   WOW! This is really interesting... tradeherpete 03/20/19 05:05:58 PM
#185954   Target around 2.55 looks about right to me, 123tom 03/20/19 05:03:45 PM
#185952   New tweet from HH about the ERP “stuff”. If kevli33 03/20/19 04:14:12 PM
#185951   More on PD and sleep. nidan7500 03/20/19 04:11:14 PM
#185950   jav0033:I’m fluent in Spanish and listened to all nidan7500 03/20/19 03:32:45 PM
#185949   Connecting the dots is all well and good jtsmgoblue 03/20/19 03:27:43 PM
#185948   The chart does not indicate the interval used, XenaLives 03/20/19 03:25:00 PM
#185947   I hear ya...I would love to see that Irishmick8299 03/20/19 02:51:37 PM
#185946   2.55 is a good mark. pcguy 03/20/19 02:39:48 PM
#185945   A hostile takeover does not imply that a imho 03/20/19 02:29:02 PM
#185944   Yep. AVXL did all 3 today. rayovacAAA 03/20/19 02:24:42 PM
#185943   I can understand the frustration considering the previous vg_future 03/20/19 02:21:22 PM
#185942   I'm fluent in smirks, 123tom 03/20/19 02:13:19 PM
#185941   Thank you for clarifying, sounds great to me!!! bennyboy1 03/20/19 02:11:18 PM
#185940   jav---"I’m fluent in Spanish"--thanks for your report !!!!! plexrec 03/20/19 02:06:19 PM
#185939   True, although the 3rd option is the most Cbdpotential 03/20/19 02:03:06 PM
#185938   .09c spread...hmmmm Lima4918 03/20/19 02:02:31 PM
#185937   The increased number of posts with the intent rocalinda 03/20/19 01:58:25 PM
#185936   A hostile takeover does not imply that a XenaLives 03/20/19 01:56:54 PM
#185935   The body language between all 3 panelists seemed FitzyP33 03/20/19 01:55:17 PM
#185934   I’m fluent in Spanish and listened to all jav0033 03/20/19 01:53:48 PM
#185933   Let’s all vote for preferred passage so we imho 03/20/19 01:38:54 PM
#185932   Excellent t nidan7500 03/20/19 01:30:06 PM
#185931   Keep ears and eyes wide open. I truly raja48185 03/20/19 01:26:03 PM
#185930   Excellent t Thank you for your translation Now Flying Albatross 03/20/19 12:48:06 PM
#185929   Not rumor.It was said for the doctor of ElsaSara 03/20/19 12:40:50 PM
#185928   Keep ears and eyes wide open. I bennyboy1 03/20/19 12:34:23 PM
#185927   Dr.M. had a lot to say, but he Bourbon_on_my_cornflakes 03/20/19 12:29:59 PM
#185926   expression on his face was probably his way nidan7500 03/20/19 12:24:45 PM
#185925   Follow the Yellow Brick Road to destination! bennyboy1 03/20/19 12:17:07 PM
#185924   That stoic expression on his face was probably XenaLives 03/20/19 12:16:08 PM
#185923   Dr Senge describes the principal of leverage in nidan7500 03/20/19 12:07:58 PM
#185922   Retail has a poor track record of voting XenaLives 03/20/19 11:47:30 AM
#185921   Yeah. The motion didn't pass. If sufficient Steady_T 03/20/19 11:31:13 AM
#185920   I think the news is great, don't get pcguy 03/20/19 11:29:47 AM
#185919   Another priceless bit of leadership strategy here w/organizing Bourbon_on_my_cornflakes 03/20/19 11:13:49 AM
#185918   Looks like Investor's sideways, up or down forecast IhidfromtheX 03/20/19 10:59:27 AM
#185917   Another priceless bit of leadership strategy here w/organizing nidan7500 03/20/19 10:59:19 AM
#185916   Shareholders did not say no in the past... XenaLives 03/20/19 10:57:31 AM