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Anavex Life Sciences Corp (AVXL)

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Last Post: 2/21/2018 10:17:18 AM - Followers: 714 - Board type: Free - Posts Today: 41

Anavex Life Sciences Corp (AVXL)

Company website:
Company Address:
51 West 52nd Street, 7th floor
New York, NY
10019 USA

CIK:  0001314052

Anavex®Life Sciences Corp. (the “Company”) is a clinical stage biopharmaceutical company engaged in the development of differentiated therapeutics for the treatment of neurodegenerative and neurodevelopmental diseases including drug candidates to treat Alzheimer’s disease, other central nervous system (“CNS”) diseases, pain and various types of cancer.  The Company’s lead compound ANAVEX®2-73 is being developed to treat Alzheimer’s disease, Parkinson’s disease and potentially other central nervous system diseases, including rare diseases, such as Rett syndrome.

Anavex®Life Sciences’ lead drug candidate, ANAVEX®2-73, recently completed successfully a Phase 2a clinical trial for Alzheimer’s disease.  ANAVEX®2-73 is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors.  Preclinical studies demonstrated its potential to halt and/or reverse the course of Alzheimer’s disease. It has also exhibited anticonvulsant, anti-amnesic, neuroprotective and anti-depressant properties in animal models, indicating its potential to treat additional CNS disorders, including epilepsy and others.  The Michael J. Fox Foundation for Parkinson’s Research has awarded Anavex® a research grant to develop ANAVEX®2-73 for the treatment of Parkinson’s disease to fully fund a preclinical study, which could justify moving ANAVEX®2-73 into a Parkinson’s disease clinical trial.  ANAVEX®3-71, also targeting sigma-1 and M1 muscarinic receptors, is a promising preclinical drug candidate demonstrating disease modifications against the major Alzheimer’s hallmarks in transgenic (3xTg-AD) mice, including cognitive deficits, amyloid and tau pathologies, and also with beneficial effects on neuroinflammation and mitochondrial dysfunctions.

The Company is in preparation for ANAVEX®2-73 for a Phase 2/3, placebo-controlled trial in Alzheimer’s disease as well as a Phase 2, placebo-controlled trial in Rett syndrome, for which the U.S. Food and Drug Administration (FDA) granted Orphan Drug Designation (ODD) for ANAVEX®2-73 and a Phase 2, placebo-controlled trial in Parkinson’s disease.

Headquartered in New York, Anavex® Life Sciences is an American publicly traded corporation on Nasdaq quoted as AVXL


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Clinical Trials:
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AVXL News: Amended Statement of Ownership (sc 13g/a) 02/14/2018 05:49:32 PM
AVXL News: Anavex Life Sciences to Present at the 2018 BIO CEO & Investor Conference 02/08/2018 07:00:00 AM
AVXL News: Quarterly Report (10-q) 02/07/2018 05:05:16 PM
AVXL News: Anavex Life Sciences Provides Clinical Programs Update and Reports Fiscal First Quarter 2018 Financial Results 02/07/2018 07:00:00 AM
AVXL News: Anavex Life Sciences to Announce Fiscal First Quarter 2018 Financial Results and Provide an Update on Clinical Programs and C... 02/05/2018 07:00:00 AM
PlusOneCoin Top Posts
#141363   DD re: discussion of genome sequencing database: This is Biostockclub 02/16/18 04:07:56 PM
#141267   “Fluvoxamine (SSRI) 17.0 F1ash 02/16/18 09:14:19 AM
#140595   I did have faith, for 2years. Don't like CashMoney75 02/11/18 12:11:09 PM
#141363  Sticky Note DD re: discussion of genome sequencing database: This is Biostockclub 02/16/18 04:07:56 PM
#139203  Sticky Note Adaptive Trial Design - what is it and Investor2014 01/31/18 05:40:05 AM
#137176  Sticky Note Flash if you’ve questions and concerns about our polarbear77 01/12/18 11:19:13 AM
#135567  Sticky Note Good lessons learned from AVXL investment in 2017. Rising_Sun 12/29/17 02:53:39 AM
#129044  Sticky Note People seem to always lose track of the dadofmarcmax 11/06/17 10:58:33 AM
#141940   Even as the resident skeptic I have to LakeshoreLeo1953 02/21/18 10:39:18 AM
#141939   The Rett IND must have been filed in BIOChecker4 02/21/18 10:35:05 AM
#141938   Consider a different point of view. mapman1010 02/21/18 10:17:18 AM
#141937   Biogen's CEO is a first timer, too, as powerwalker 02/21/18 10:00:45 AM
#141936   "Please explain to all of us how Anavex flsh56 02/21/18 09:55:31 AM
#141935   I believe that you and xena nailed it, polarbear77 02/21/18 09:52:39 AM
#141934   i like the F-4 Phantom. Loud and scary. indebt2 02/21/18 09:48:06 AM
#141933   so we(i used to) will take most anything nidan7500 02/21/18 09:22:55 AM
#141932   Ahhh, this is gonna take a while...a quick nidan7500 02/21/18 09:13:03 AM
#141931   SirChar--"Wake me up when AVXL starts a trial."---have plexrec 02/21/18 09:09:23 AM
#141930   If I were a goal oriented Type A LakeshoreLeo1953 02/21/18 09:03:26 AM
#141929   i am very sorry to hear about your mapman1010 02/21/18 08:56:07 AM
#141928   The case for RWE is being built by FDA...OK nidan7500 02/21/18 08:48:12 AM
#141927   Same document - used the pre inside of XenaLives 02/21/18 08:45:13 AM
#141926   i got ya jimmy. your response was to mapman1010 02/21/18 08:42:42 AM
#141925   Well said Cbdpotential 02/21/18 08:26:54 AM
#141923   The new regs./guidance also explain why so many nidan7500 02/21/18 08:02:28 AM
#141921   Ever notice how certain terms begin to reappear nidan7500 02/21/18 07:55:14 AM
#141917   So it must be useful to someone nidan7500 02/21/18 07:24:53 AM
#141916   Humira is a MAB with all kind of nidan7500 02/21/18 07:22:07 AM
#141915   If 273 is the wonder drug everyone thinks Fireman02360 02/21/18 07:20:58 AM
#141910   End of the year????is that where we are Hagrid 02/21/18 06:50:44 AM
#141909   Talon, I am starting to feel I need powerwalker 02/21/18 06:08:05 AM
#141905   I concede to Mapman and your greater knowledge jimmy667 02/21/18 03:17:18 AM
#141904   "Iron Hand" Wild Weasel Thuds trolling for SAMs jimmy667 02/21/18 01:25:10 AM
#141903   Jimmy, Just like the Lockheed "Skunk Works" designed Talon38 02/21/18 12:49:43 AM
#141902   No. A2-73 has been engineered to fly. A2-73 jimmy667 02/21/18 12:19:08 AM
#141901   We will find out when they release the Turner2017 02/21/18 12:07:11 AM
#141900   111 or 777? B777 powered by specially designed jimmy667 02/21/18 12:02:54 AM
#141899   There are 40,000,000 shares in public trade.. even McMagyar 02/20/18 11:38:46 PM
#141898   Anything is possible. Biogen was once trading at Turner2017 02/20/18 11:20:19 PM
#141897   I am all about dreams coming true. RJ Trotts 02/20/18 11:14:09 PM
#141896   Not a fan of 273 and I don ExtremelyBullishZig 02/20/18 10:01:51 PM
#141895   You seem frustrated. I get it. polarbear77 02/20/18 10:00:33 PM
#141894   I am sure the FDA application/protocol could not ExtremelyBullishZig 02/20/18 09:59:28 PM
#141892   Nice McMagyar 02/20/18 09:44:37 PM
#141891   Call me crazy but I had a dream Turner2017 02/20/18 09:44:12 PM
#141890   I think some other company figured out how SirCharChar 02/20/18 09:40:24 PM
#141889   Wake me up when AVXL starts a trial...if SirCharChar 02/20/18 09:36:05 PM
#141888   You disparagingly accuse the Company of paralysis of polarbear77 02/20/18 09:33:58 PM
#141887   Yeah, sure they did... basparks79 02/20/18 09:23:25 PM
#141886   I would hope that they not ONLY use basparks79 02/20/18 09:20:17 PM
#141885   I think some other company figured out how bushman23 02/20/18 09:06:09 PM
#141884   I still think M is not sure about Amatuer17 02/20/18 08:29:27 PM
#141883   I don't think Missling is doing anything wrong, Gator328 02/20/18 08:20:19 PM
#141881   So everyone taking Aricept is smart? is ExtremelyBullishZig 02/20/18 08:01:27 PM
#141880   Lol... ExtremelyBullishZig 02/20/18 07:58:09 PM
#141879   Power, Could be that 2-73 is like Talon38 02/20/18 07:27:50 PM
#141878   The poison is generating some $16-18 Billion dollars So Amatuer17 02/20/18 07:20:23 PM
#141877   RE: Humira is a MAB with all kind Fireman02360 02/20/18 06:49:13 PM