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Anavex Life Sciences Corp (AVXL)

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Last Post: 4/26/2018 12:23:23 PM - Followers: 706 - Board type: Free - Posts Today: 53

Anavex Life Sciences Corp (AVXL)

Company website:
Company Address:
51 West 52nd Street, 7th floor
New York, NY
10019 USA

CIK:  0001314052

Anavex®Life Sciences Corp. (the “Company”) is a clinical stage biopharmaceutical company engaged in the development of differentiated therapeutics for the treatment of neurodegenerative and neurodevelopmental diseases including drug candidates to treat Alzheimer’s disease, other central nervous system (“CNS”) diseases, pain and various types of cancer.  The Company’s lead compound ANAVEX®2-73 is being developed to treat Alzheimer’s disease, Parkinson’s disease and potentially other central nervous system diseases, including rare diseases, such as Rett syndrome.

Anavex®Life Sciences’ lead drug candidate, ANAVEX®2-73, recently completed successfully a Phase 2a clinical trial for Alzheimer’s disease.  ANAVEX®2-73 is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors.  Preclinical studies demonstrated its potential to halt and/or reverse the course of Alzheimer’s disease. It has also exhibited anticonvulsant, anti-amnesic, neuroprotective and anti-depressant properties in animal models, indicating its potential to treat additional CNS disorders, including epilepsy and others.  The Michael J. Fox Foundation for Parkinson’s Research has awarded Anavex® a research grant to develop ANAVEX®2-73 for the treatment of Parkinson’s disease to fully fund a preclinical study, which could justify moving ANAVEX®2-73 into a Parkinson’s disease clinical trial.  ANAVEX®3-71, also targeting sigma-1 and M1 muscarinic receptors, is a promising preclinical drug candidate demonstrating disease modifications against the major Alzheimer’s hallmarks in transgenic (3xTg-AD) mice, including cognitive deficits, amyloid and tau pathologies, and also with beneficial effects on neuroinflammation and mitochondrial dysfunctions.

The Company is in preparation for ANAVEX®2-73 for a Phase 2/3, placebo-controlled trial in Alzheimer’s disease as well as a Phase 2, placebo-controlled trial in Rett syndrome, for which the U.S. Food and Drug Administration (FDA) granted Orphan Drug Designation (ODD) for ANAVEX®2-73 and a Phase 2, placebo-controlled trial in Parkinson’s disease.

Headquartered in New York, Anavex® Life Sciences is an American publicly traded corporation on Nasdaq quoted as AVXL


Patent Info:

Clinical Trials:
Recent News:
Company News Releases:
Share Structure:  See SEC filings
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Marketing Details:


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AVXL News: Initial Statement of Beneficial Ownership (3) 04/24/2018 12:36:08 PM
AVXL News: Current Report Filing (8-k) 04/20/2018 04:33:56 PM
AVXL News: Anavex Life Sciences to Initiate Phase 2 Study of ANAVEX®2-73 in Parkinson’s Disease Dementia and Provides Clinical Study ... 04/17/2018 07:08:03 AM
AVXL News: Statement of Changes in Beneficial Ownership (4) 03/09/2018 03:17:22 PM
AVXL News: Anavex Life Sciences to Present at the 30th Annual ROTH Conference 03/09/2018 07:00:00 AM
PlusOneCoin Top Posts
#148735   Anavex 2-73 and/or Anavex 3-71 as a potential georgejjl 04/25/18 10:04:47 PM
#148071  Sticky Note JohnJones325 shareholder meeting report... XenaLives 04/18/18 10:07:28 AM
#145269  Sticky Note Hi Nidan 7500, as it always is we The Mongoose 03/22/18 02:32:18 AM
#141363  Sticky Note DD re: discussion of genome sequencing database: This is Biostockclub 02/16/18 04:07:56 PM
#135567  Sticky Note Good lessons learned from AVXL investment in 2017. Rising_Sun 12/29/17 02:53:39 AM
#129044  Sticky Note People seem to always lose track of the dadofmarcmax 11/06/17 10:58:33 AM
#148791   Believe me, you are not alone. I bennyboy1 04/26/18 12:23:23 PM
#148790   No PR this morning so nothing of material Jimbo50 04/26/18 12:06:15 PM
#148789   As mentioned... the problem IS that the street basparks79 04/26/18 12:01:25 PM
#148788   benny...I love the science--but this $2.37 share price......I've plexrec 04/26/18 11:44:48 AM
#148787   The ONLY PR about Anavex released by RETTSyndrome LakeshoreLeo1953 04/26/18 11:37:43 AM
#148786   I believe it's because his salary really isn't Jonjones325 04/26/18 11:35:07 AM
#148785   Plex - Screw the street - sorry but bennyboy1 04/26/18 11:33:43 AM
#148784   The problem is, they are aware!!!! Mikesc 04/26/18 11:33:10 AM
#148783   11:25 eastern time 04/26/18 nidan7500 04/26/18 11:18:00 AM
#148782   "Further supporting evidence for Anavex over several CNS plexrec 04/26/18 11:17:23 AM
#148781   George and Xena you made my day! bennyboy1 04/26/18 10:49:33 AM
#148780   When the evidence is so strong that BP XenaLives 04/26/18 09:55:14 AM
#148779   Over / Under is bound to favor OVER, LakeshoreLeo1953 04/26/18 09:53:57 AM
#148778   I bet it will not happen Amatuer17 04/26/18 09:51:22 AM
#148776   Xena--" MOA effective for multiple CNS diseases, this plexrec 04/26/18 09:45:43 AM
#148775   We need to play if that is your OFP 04/26/18 09:45:23 AM
#148774   Discount Stock offerings needed imo Company just burns thru cash Sand Piper 04/26/18 09:44:46 AM
#148773   Anyone at Baccarat Table @ MGM National Harbor LakeshoreLeo1953 04/26/18 09:44:27 AM
#148772   Appears oversold to me... basparks79 04/26/18 09:41:55 AM
#148771   Good question... I'm sure the new hire basparks79 04/26/18 09:40:58 AM
#148770   What happens if the EU adds conditional approval nidan7500 04/26/18 09:34:44 AM
#148769   The eggs that this sandpiper is laying are Greenspam2 04/26/18 09:32:26 AM
#148768   PPs confirmed Downward continuation by chart indicators waaaaaaaaay overbought Sand Piper 04/26/18 09:28:21 AM
#148767   What happens if the EU adds conditional approval XenaLives 04/26/18 09:22:47 AM
#148766   When conditional approval is granted from the Rett basparks79 04/26/18 09:10:49 AM
#148764   What is with the religious shaming exercise? LakeshoreLeo1953 04/26/18 08:58:33 AM
#148762   George and Xena NICE 1-2 Combp! POW! BAM! You McMagyar 04/26/18 08:53:30 AM
#148761   “When reviewing LIFE and the goal of making Amatuer17 04/26/18 08:52:08 AM
#148760   Hi jj325 Thank you for your reply the other Flying Albatross 04/26/18 08:52:03 AM
#148759   Thanks fireman! What great info! Everyone should check McMagyar 04/26/18 08:45:15 AM
#148758   How was that for a non Technician with LakeshoreLeo1953 04/26/18 08:43:43 AM
#148757   I think you'll find the clue here, all XenaLives 04/26/18 08:42:05 AM
#148756   Well it’s called LIFE And as we all know McMagyar 04/26/18 08:38:38 AM
#148755   Hey Piper, the sand in your eyes makes Greenspam2 04/26/18 08:36:10 AM
#148754   We have Guaranteed buyers for 5 million shares! McMagyar 04/26/18 08:33:35 AM
#148753   Bumping this post - it supports AVXL MOA XenaLives 04/26/18 08:28:06 AM
#148752   I dont like shorting. IMO it should be Plato7 04/26/18 08:21:28 AM
#148751   Chart clearly bearish +heading lower link: Sand Piper 04/26/18 07:58:48 AM
#148748   company burning $$ 4m a qtr no revenues no Sand Piper 04/26/18 07:33:51 AM
#148747  Restored HUGE downward gap-fill 1.85 heres ur link: see Sand Piper 04/26/18 07:31:20 AM
#148746   Deuterated drug is a small molecule medicinal product XenaLives 04/26/18 07:13:36 AM
#148745   Excerpt from your article: XenaLives 04/26/18 07:04:51 AM
#148744   Wrong again Mr. Sand Piper. Considerable drop in Fireman02360 04/26/18 06:50:23 AM
#148743   So what happened to AD trial and Anavex Amatuer17 04/26/18 05:56:22 AM
#148742   deuterated PUFA ..sounds like a sad PUFA to McMagyar 04/26/18 01:48:04 AM
#148741   great news! More buyers guaranteed! McMagyar 04/26/18 01:33:10 AM
#148740   Shorts continue to add positions Sand Piper 04/26/18 12:39:12 AM
#148736   Thank you, Investor. basparks79 04/25/18 10:07:54 PM
#148735   Anavex 2-73 and/or Anavex 3-71 as a potential georgejjl 04/25/18 10:04:47 PM
#148731   A profound observation, indeed! It’s an extraordinary sokol 04/25/18 09:37:54 PM