Anavex Life Sciences Corp (AVXL)

[poguemahone]

Sure hope you are proven correct. I feel confident until Missling opens his mouth and speaks, and then those nagging doubts creep back in.

[williamssc]

The January J.P. Morgan Healthcare Conference brought in smart investment bankers.

[falconer66a]

Longterm, Utility Numbers Don't Crunch, Compete with Anavex

If dividends are your thing, utilities are a better option.

I don't think so.

Compared to an eventual 100 million outstanding shares of AVXL, I've run the numbers on Anavex's potential annual revenues once they get one or two of their drugs approved to treat or prevent just a few of the diseases and conditions the company is targeting with blarcamesine and Anavex 3-71. Tens of billions of revenue dollars. Per-share annual revenues will be gigantic.

So, you think I'll be screwed if Anavex decides to hold gigantic cash accumulations and pay out tiny or absent dividends? If so, I won't be locked into a "hold 'em all" position. What do you suppose will happen to the AVXL share price if the company is taking in multiple billions without paying ample dividends? Will it stagnate at, say, $50? Or, go up somewhere into three digits?

Surely, if Anavex levels out with annual revenues of tens of billions but fails to pay out ample dividends, be assured, I'll recognize the situation and start selling small portions of my then gigantic AVXL position to gain cash in my bank account. That's when I might invest some of those dollars in some good utilities. Not until then. But probably never, as Anavex actually will eventually pay real, ample dividends. Better than any utility company or ETF.

[Steady_T]

Bio techs may get funding from those firms but so far there is no evidence that Anavex is getting funding from those firms.

You fascination with advanced degrees is misplaced confirmation bias.
I have run across several people that haven't learned anything once they got out of school. And at the opposite end of the spectrum are the people that I have met that never quit learning once they left school.

While formal education is one path to knowledge and thinking skills it is by no means a guarantee of skills, there are other paths that lead to great results.

Science is full of people that had degrees in one area and the person worked in that area for while and then got exposed to a different unrelated area, decided to pursue it and self educated to become expert in that area.

Use your head and allow others to use theirs, with or without advanced degrees.

[kund]

Yep, it has been safe for Misleading's pocket.

[bb8675309]

Blarcamesine is proven safe in over 9 years of drug trial results and endorsed by 58 of the world best doctors / scientists after a peer review study. This drug should immediately be approved for Alzheimer's and Dementia patients treatment world wide. Safest CNS drug ever invented to date. Imo

The Journal of Prevention of Alzheimer's Disease
Volume 12, Issue 1, January 2025, 100016

"The objective of this study was to assess efficacy and safety of blarcamesine (ANAVEX®2-73), an orally available small-molecule activator of the sigma-1 receptor (SIGMAR1) in early AD through restoration of cellular homeostasis including autophagy enhancement".

https://www.sciencedirect.com/science/article/pii/S2274580724006083

[poguemahone]

You keep mentioning future cash dividends from this stock as one of your motivations for investing in this stock. While I hope you are correct (and I will gladly give you a mea culpa one day), SP appreciation is the more likely scenario for your wealth accumulation. Dividends are not the preferred method of pharmaceutical companies to invest their retained earnings, since they are continuously looking to reinvest in new drug development to offset patent expiration. If dividends are your thing, utilities are a better option.

[kund]

You're cherry-picking data, just like Misleading does with his trials. There are companies with over 80% institutional ownership that have still gone bust. Institutions are also shooting in the dark.

Below is institute ownership over last one year:

Q4 23: 36%
Q1 24: 42.95%
Q2 24: 37.53 %
Q3 24: 39.16%
Q4 24: 40.74%
Q1 25: 42.92%

Institutions can bail out without any notice.

[k9uwa]

YES FRROL tell us why 42% of AVXL stock is owned by Institutions. That is a substantial INCREASE during Q1 2025 over what they held Q4 of 2024. Now we are a bit over 1/2 way through Q2 2025 and have observed near daily large quantity of AVXL shares traded as MOC orders. 50,000 75,000, 100,000 shares in single trades. A couple days also rather large 40,000 share MOO orders. Are those Institutions all Dumb like Boxes of Rocks? I don't think so.

https://fintel.io/so/us/avxl

John k9uwa

[k9uwa]

Count me out as well.

AVXL Already made a large BUNDLE OF CASH. Expect to get a LOT MORE IN THE NOT TOO DISTANT FUTURE.

maybe Febish as some call it.
John k9uwa

[falconer66a]

Trading, Liquidation, or Dividends?

I may or not trade AVXL successfully over the next 9-12 months, but IMO the Market will give us roughly that time period to commit to or exit the play.

Until then GL with your decision making.
Conversely, my best wishes for your strategy.

For those who have taken an AVXL position, there are a number of approaches for this.

Some see the price variations of AVXL as an opportunity to make dollars by artful trading. The buy low and sell high approach — many times, from day-trading on up to longer trade periods. Long term traders are holding for some future liquidation trade, at a price much higher than their purchase prices. Perhaps a few buys, then later a single big-time exit and profit.

Then there is the future dividends perspective, where an AVXL position is taken and held in anticipation of the time Anavex Life Sciences Corp pays substantial dividends. In this approach AVXLs are held, not traded. Gains will be solely from future dividend payments, not equity sales.

From my start, that’s been my position. In a few years I anticipate that Anavex Life Sciences Corp will be a payer of substantial dividends. At that time I’ll have two strong values from my several thousand shares of AVXL: rewarding annual dividends, while my estate owns the position, which will then be distributed to my beneficiaries at my demise.

But if Anavex fails to get any of its drugs approved for any disease indication the value of my AVXl position will sharply descend, whereupon I’ll liquidate the position at a price about 25-cents above my cost basis. A win or break even approach.

[LakeshoreLeo1953]

Is AVXL the stock a better gamble than upon NASDAQ listing?
I think that answer is yes.
If nothing else there is a more reasonable timetable for what is most likely a binary outcome.
Does that make all “institutional” involvement a signal of guarantee?
I think not. If you assume those adds cited are not one individual, but a basket of clients then at least three or more posters here claim to rival those holdings. Some have expressed monotonous support since SP 20+.

I may or not trade AVXL successfully over the next 9-12 months, but IMO the Market will give us roughly that time period to commit to or exit the play.

Until then GL with your decision making.
Hopefully you keep it informed and adaptive.

[LakeshoreLeo1953]

I have EXPECTED each of my trades to perform positively
OR
I wouldn't make them!!!!
Am I correct 100% of the time? Of course not.
Have my efforts out performed set it and forget it investing?
Most definitely.
It is not so much that I await a certainty of a marketable product.
I anticipate further Market opportunities in the SP of AVXL.

Benefit to ALZ sufferers and their families? Hopefully!!!

[frrol]

Your reasoning is poor, and you still don't understand why, even after it's explained to you. Read it again.

Not impressive, Ima.

[Investor2014]

So blarcamesine is not withdrawn yet.

[falconer66a]

Ok, But Tell Us Why They Purchased....

Be careful with delusional knuckleheads on messageboards, everyone.

As always, readers were impressed with your adroit posting.

But, please tell us, exactly why did those hedge funds spend so much on those big AVXL purchases? Were those hedge fund managers “knuckleheads,” or what? Better than anyone you know why. Please tell us. Most of us think they see a bright future for Anavex Life Sciences Corp.

[frrol]

Ima Biologist Valid Proclamation lol

Biotechs get funding from these firms. Some succeed, most unfortunately fail. Biotechs do animal testing. Some pan out in humans with actual disease, most unfortunately fail. Confirmation bias is for fools. And true biologists, with advanced degrees and research experience, are trained enough and wise enough to avoid it. Be careful with delusional knuckleheads on messageboards, everyone. Use your heads.

[tredenwater2]

Great nugget hnbadger! What do you think was going through the mind of the US congressman when Anavex representatives sit across from him and share their drugs benefits including safety? On one hand he is elated at the “recent”breakthrough science. On the other hand he knows the enormous lobbying power of big pharma.
If ever there was a prime time and a “prime bill” ,Sen Ted Cruz’s, now is the time!

Time to prime the engine and pull the rope and see if she fires!

[poguemahone]

An empty suit speaking in an empty room. That sounds about right for Missling.

I have viewed these investor conferences that Missling attends as nothing more than quarterly CC bullet material. These give the illusion that Missling is actively stating the company’s story to Wall Street. The languishing SP tells anyone willing to listen all they need to know.

[kund]

Someone posted a picture from the HCW conference on ST—it looks identical to Misleading's last HCW conference. The first couple of rows appear completely empty. Did he end up speaking to an empty room?

[Steady_T]

Count me out of that group.

AVXL has made me money.
And I expect it to make a lot more for me.

[mike_dotcom]

I often ask myself the same question.

[Lacey1]

Then why are you in it. Buy bitcoin or antique cars. You are the whiniest message board poster to date.

[jb23456]

hi i am on a pixel 9 but i cannot see the spreadsheet? Can someone repost?

[BDR10]

I don't know one person that's ever expected anything from this stock that wasn't totally disappointed

[k9uwa]

Another day with 90,000 shares MOC.Gary your correct. Same rule applies to Real Estate said me the Landlord.
John k9uwa

PriceSizeTypeTime
7.53 1 Odd lot 16:04:08
7.53 1 Odd lot 16:04:04
7.53 1 Odd lot 16:04:04
7.53 1 Odd lot 16:04:03
7.53 2,412 prior ref 16:02:00
7.53 1,366 prior ref 16:01:41
7.53 619 prior ref 16:01:28
7.53 122 prior ref 16:01:16
7.53 75 Odd lot 16:01:14
7.53 352 form t 16:00:08
7.53 1,547 form t 16:00:08
7.53 3,200 form t 16:00:04
7.53 4,632 form t 16:00:04
7.53 109 form t 16:00:00
7.53 49 Odd lot 16:00:00
7.53 1 Odd lot 16:00:00
7.53 77,045 16:00:00
7.53 77,045 16:00:00
7.53 100 16:00:00
7.51 17 Odd lot 16:00:00
7.52 23 Odd lot 15:59:59
7.52 68 Odd lot 15:59:57
7.53 100 15:59:57
7.53 18 Odd lot 15:59:57
7.53 59 Odd lot 15:59:57
7.51 35 Odd lot 15:59:56
7.52 65 Odd lot 15:59:56
7.52 17 Odd lot 15:59:56
7.53 42 Odd lot 15:59:56
7.53 27 Odd lot 15:59:56
7.52 87 Odd lot 15:59:56
7.52 5 Odd lot 15:59:56
7.52 37 Odd lot 15:59:56
7.52 75 Odd lot 15:59:56
7.52 77 Odd lot 15:59:55
7.52 43 Odd lot 15:59:55
7.52 4 Odd lot 15:59:55
7.52 100 15:59:55
7.53 2 Odd lot 15:59:55
7.52 1 Odd lot 15:59:55
7.53 24 Odd lot 15:59:54
7.52 100 15:59:53
7.52 100 15:59:53
7.52 106 15:59:52
7.52 13 Odd lot 15:59:52
7.52 2 Odd lot 15:59:52
7.53 100 15:59:52
7.53 43 Odd lot 15:59:52
7.53 21 Odd lot 15:59:52
7.53 31 Odd lot 15:59:52

[georgejjl]

The treatment of participants in the Phase 2 schizophrenia trial will be complete the week after next week.

Expect top line results by or before the end of July 2025.

Good luck and GOD bless,

[mike_dotcom]

Thank goodness for holidays. That's one day next week I know this POS won't go down.

[k9uwa]

Leo go down page and read my previous post from a few hours ago. It will tell you exactly where those two Tutes stand holding AVXL stock.
John k9uwa

[skitahoe]

In the life of just about every biotech there will be a lot of ups and downs. If you're a long investor and the company achieves success, you'll do well just buying, holding, and adding more on weakness. If you're a trader, if you're good at guessing where the ups and downs are, and you're right, you can make more than a buy and hold strategy. If you're wrong, however, you could miss out on a massive gain and those simply holding end up well ahead.

Personally, I hope that after a really big gain that I'll hold, and sell out of the money calls for pocket change on not more than a small percentage of my holdings. If I'm right and the stock retrenches after the gain I'll either buy back the calls at much lower price or let them expire. Then do it again on the next major gain. I'm not looking to sell, but rather to pass the stock on to my daughters, who'll get a new price basis once I'm no longer here. I'm in my 80's and while I hope it's no time soon, as long as I have all I need without selling, why not give them the advantage, and not have to be taxed on the gain.

If you're actively trading, taxes should be a consideration in all the trading. I know the brokeage, and your accountant will handle it, but it's not a big profit if Uncle Sam takes a big chunk out of it.

Gary

[cfoofme]

Speaking of bioturds , bioturd AF has been the deranged leader of the lying bioturd club since I first saw his first article many years ago.

[kund]

The WGT crowd initially claimed Misleading wasn't filing with the FDA due to draft guidelines on endpoints. Now the theory is that he's waiting for the reciprocal approval law from Cruz and company, so he sent his squeeze to DC to suck them dry. But the U.S. is a sovereign nation, no strong and functioning sovereign country delegates drug approval to a third country. Even the EU doesn’t automatically approve FDA-approved drugs.

[bb8675309]

Obvious Manipulation. 670 Million Market Cap. Ridiculous.

[kund]

AF on X "There comes a point in the lifecycle of every bioturd where our anger / outrage turns to bemusement / laughter. These companies become jokes.

We used to get mad about $SAVA $NWBO $CVM $AVXL etc. Now, we just mock them because that's all they're good for."

[sab63090]

Leo
Although I can't deny that the stock broke down thru prior supports (I.e...the 200 day and very minor below the prior low on April 9th ($7.26).....we traded to a low just 3 days ago @ $7.16....a lousy 10 cents lower. Some traders would call that a potential double bottom or a terminal shake out or turtle soup low.

For now and until I am proven wrong, I will stick with the idea that $7 needs to hold....along with a positive divergence with the RSI....stock went lower, RSI did not. The RSI is MOST USEFUL when it shows a positive divergence on low or negative divergences on highs.

$8 should be the change from down to up and breaking the 200 day and eventually the 50 day would be SWEET......with volume!

🤠

[LakeshoreLeo1953]

One would need to consult the Ouija Board or Magic Eightball
in this volume Market to divine a direction and support for AVXL.

[LakeshoreLeo1953]

None of those YTD statistics looks anywhere near 90%
unless you stretch the negatives a bit..

[LakeshoreLeo1953]

I don't have a clue what their strategy was in those purchases.
Do You?
Are the "Long and Strong" WGT?
Are they hedging the position?
Was the promise to clients a "safe as Treasuries" assurance?

Inquiring minds would love to know that due diligence.

[k9uwa]

Thanks Flakes. Balyasny Asset holdings of AVXL Previous to Q1 2025 they had ZERO AVXL. End of Q1 171,383 long shares. 390,000 shares Calls

BALYASNY ASSET MANAGEMENT L.P. History 171,383 1,470,466 0.00% 1842 171,383 New 0.20% Q1 2025 9.43 13F Filing 2025-03-31 2025-05-15
BALYASNY ASSET MANAGEMENT L.P. CALL History 390,000 3,346,200 0.01% 1445 390,000 New Q1 2025 13F Filing 2025-03-31 2025-05-15

LPL 546,626 total of which during Q1 they bought 452,723 shares.

They are definitely here to make $$$$
John k9uwa

[hnbadger1]

https://www.ema.europa.eu/en/news/meeting-highlights-committee-medicinal-products-human-use-chmp-19-22-may-2025

[crescentmotor]

This drop is just ghastly shorts can cover easily at this level

The question is: will they? In the available data to date, the number of shares shorted has barely dropped.

[mike_dotcom]

They covered over a million shares between the last reports without making the stock go UP. The stock market is a giant scam.

[Bourbon_on_my_cornflakes]

This drop is just ghastly
shorts can cover easily at this level

[mike_dotcom]

Yea, no hedge fund has ever bought a losing stock.

[falconer66a]

Was There Any Due Diligence?

LPL Financial bought 453K shares of AVXL last qtr.

Balyasny Asset Management bought over 500K AVXL shares last qtr.

What could these hedge funds have been thinking? They take in, handle, and trade millions of dollars for their well-heeled clients. Why, ever, would they plunk down those dollars to take large AVXL positions? If these 953,000 AVXL shares were purchased at $8.00, $7,624,000 was spent.

You’d think that big-spending hedge funds such as these would do their due diligence before taking positions as questionable as AVXL. What, perchance, could have prompted these purchases? Clearly, they don’t read, know, or understand what we learn here from our doomsaying Anavex experts each day.

[tschussmann1]

Picked up a few pre-market. Still have the lower rungs of the ladder if it gets taken down further. OK if they get filled, OK if not. The only thing that really matters is EMA approval. Obviously, I expect this to occur. Sigma-1 science is real.

[LakeshoreLeo1953]

"By George...I think she's got it"!!!!
(slight paraphrase)
Age test...Who and where??? Hint movie.

[LakeshoreLeo1953]

2.5% chance to "visit" one of your hotels?
AND a few "rolls" to get there from GO.
Even Doc thinks Anavex has better chance than that with EMA.

[mike_dotcom]

I sure hope all this positivity doesn't lead us to another 10% haircut today.

[hnbadger1]

MayoMobile on stock twits-
$AVXL Nell Rebowe ostensibly attended probable roundtable, meeting, lobbying, etc. in the Rayburn House Office Building earlier today.
This facility hosts the House Committee on Energy and Commerce - the most influential House committee for pharmaceutical and biotech legislation, amongst other notable committees.
This repeated attendance in DC makes me wonder if Anavex is actively seeking to support Ted Cruz's RESULT Act.
"The bill is primarily aimed at smaller companies, which have a harder time than larger manufacturers navigating and paying for the FDA approval process,"
"The FDA's approval process has kept many useful drugs and devices from Americans for decades while adding enormously to the cost, so that only potential blockbusters can be brought to market," said Jane Orient, M.D., executive director of the Association of American Physicians and Surgeons. "Yet, many have had to be withdrawn for adverse effects that became apparent later, some of which had been concealed."