1) "it's not about the RRR and the P value... It's about the number of events in the data points". you think they'll approve even if not stat sig on the primary endpoint? (Um, very unlikely)
2) "We already know the RRR is going to be fine". Two responses: I think that is a bizarre statement about a blinded trial. Also, if you are sure RRR is going to be fine, then why did you just excuse a missed p value?