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08/12/17 2:04 PM

#129692 RE: flipper44 #129688

You and I have always thought that when they report any results, they should take care to point out that there is also 3 months pipeline that would add 3 months to any treatment to event results.

The 11th slide in Dr. Bosch's ASCO presentation delineates and makes clear that approximate 12 week (3 month) screening process. And he referenced it several times in his presentation. So I think they realize the need to make this clear.

But what I did was simply use the hypothesized numbers that they presented in the protocol, and step by step showed at what time (based on those numbers) we might expect the 248 patients that were enrolled in the trial by February 2015 to have reached a PFS event, had they all evented.

Interestingly, it was at the same time they announced that 248 PFS events had been reached.

I'm sure that those 248 final event numbers didn't all come from the 248 patients enrolled by February 2015. There would have been some numbers coming from patients who enrolled after that. But this was based on averages, and so basing it on averages would account for that.