Avid Bioservices Inc (CDMO)

[biopharm]

Must Read: Dengue Fever : Hyeryun Choe (presenting 4/1 @Keystone re: PS Targeting : [color=red][/color]

Pay attention to "This is where the trouble begins" .... our time is getting ever so much closer and right on target for the Keystone Symposia where Associate Professor Hyeryun Choe will be talking "SPECIFICALLY" about PS targeting.... all Bavi backers have to love this as the spotlight is about to get a little brighter and more focused on PS targeting and exactly "... where the trougble begins"

Scripps Florida scientist awarded $2.3 million to study dengue fever and related viruses

March 27, 2014

Now, scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded $2.3 million to study a category of viruses that cause dengue fever, West Nile, yellow fever and other diseases spread by mosquitoes and ticks. These diseases can result in flulike symptoms, extreme pain (dengue has been called "bone-break fever") and, in some cases, encephalitis.

This family of viruses, called "flavivirus," affect some 2.5 billion people worldwide and cause hundreds of thousands of deaths each year. There are no antiviral treatments and a just handful of vaccines that provide protection against only a few of these diseases.

The principal investigator for the new five-year study is TSRI Associate Professor Hyeryun Choe, who will lead the effort to understand the virus's mode of infection and how new therapies might interrupt it.

"Flavivirus uses a very clever method of infection," Choe said. "It's like using a side door to enter a house when the front door is locked."

The viruses take advantage of the process that normally occurs during programmed cell death. During programmed cell death ("apoptosis"), a lipid usually found on the inner side of the cell membranes, specifically phosphatidylserine (PS), shifts to the surface, making itself readily available to any passing cellular stranger. This is where the trouble begins.

When cells are dying from a flavivirus infection, their freshly exposed PS is grabbed by the exiting virus, and phagocytescells that devour invading pathogens and dead and dying cellsengulf the virus as if it were a dying cell. O

http://www.bio-medicine.org/medicine-news-1/Scripps-Florida-scientist-awarded--242-3-million-to-study-dengue-fever-and-related-viruses-125624-1/

and again... thanks to Volgoat for picking this up way back on March 12, 2014:
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http://investorshub.advfn.com/boards/read_msg.aspx?message_id=98718384&txt2find=choe