Medizone Intl. (fka MZEIQ)

[Tane61]

Update on "no touch" room disinfection systems - uv lights, hydrogen peroxide and ozone

Dick Zoutman

(excerpt)

"Interpreting Results

"• Surface swabs

"– Typically expressed as cfu/cm2

"• Typically see 10’s to 100’s cfu/cm2"

http://www.picnetbc.ca/webber-training

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MERCURY UVC

(Zoutman referenced study)

Room Decontamination with UV Radiation
William A. Rutala, PhD, MPH; Maria F. Gergen, MT (ASCP); David J. Weber, MD, MPH

Discussion (excerpt)
"The system that we evaluated is unique in that it uses measured UV-C intensities reflected from the walls, ceilings, floors, or other items in the room and calculates the operation time required to deliver the programmed lethal dose for microorganisms.8

"The ability of the device to deliver lethal doses of UV-C to epidemiologically important microorganisms on nonreflective surfaces was evaluated, and we found that the quantities of these organisms were significantly reduced, re-producibly by 3–4 log10, under high contamination levels that exceed the levels normally found in healthcare facilities. In fact, studies have shown that, although the frequency of contamination by these pathogens (eg, C. difficile) is high (10% to more than 50%, the microbial load is generally low (less than 10 to 100 CFUs per plate or sample).13

"During the second phase of the study, we studied situations in which the bioburden levels are those naturally found on surfaces. In these situations, UV-C is capable of completely inactivating the entire population of vegetative bacteria (eg, MRSA or VRE) within approximately 15 minutes."

Acknowledgments
"We thank Lumalier Corporation for loaning UNC Health Care the UV device used in these experiments."

http://www.jstor.org/stable/pdfplus/10.1086/656244.pdf

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IF YOU CAN'T BEAT THEM...

http://www.pathogon.com/

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PULSED-XENON UV

Quote: "Xenex guarantees that in each room where the Xenex treatment is used, all of the high-touch surfaces (those surfaces which are known to have an impact on the hospital infection rate) will be 100% pathogen-free. Furthermore, the speed of the pulse xenon equipment allows Xenex to disinfect the patient environment without disrupting patient throughput or other operations."

Xenex Successfully Completes Materials Test
Saturday, June 27th, 2009

"Xenex completed a test to assure that the UV emitted during a standard treatment would not damage common materials in healthcare settings. During the test, over a dozen materials commonly found in hospital rooms were exposed to a three-year equivalent of UV dosage. The results found no detectable damage in both visual and tactile testing for all the materials with the exception of slight fading of paper products.

"Materials tested include rubber bumper materials, o-rings, rubber gloves, paint samples, tile, white paper, business cards, assorted tubing, screens from cell phones and electronic devices and other materials. No detectable changes were found when comparing the exposed surfaces to unexposed, with the exception of a slight fading of the paper products. The fading was only recognizable when compared side by side to the unexposed sample.

"Overall, the duration of UV exposed is under two minutes for the entire three-year equivalent period. This is because each of the pulses of the Xenon lamp is milliseconds in duration. UV damage is minimized by this process when compared with other UV technologies such as continuous mercury UV lamps."

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VHP (35% H2O2)

Material compatibility? ("WET" versus "DRY" - http://bioquell.idmpreview.co.uk/new/Resources/Bioquell%20WetDry%20Leaflet1.pdf)

Quote: "STERIS has sold thousands of VHP-based systems around the world. They create validated clean room environments on a daily basis for FDA-regulated pharmaceutical production and laboratory operations. Well-known for its wide range of material compatibility, VHP is recognized as the gold standard for aseptic pharmaceutical production environments." (http://www.steris.com/products/equipment-decontamination/vaprox-hydrogen-peroxide-sterilant)

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Zoutman needs to update the machine graphic (see video)

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AEROSOL - SMDF™ (Sub-Micron Dense Fog) - (0.18% PAA + 0.88% H2O2)

Altapure's process delivers 6+ Log reduction in less than 10 minutes of exposure. Treated surfaces are proven to show “no growth” for bacterial spores, vegetative bacteria, and virus, within the treated space. Altapure's process has a D-Value of 2.3--2.6 minutes for Geobacillus stearothermophilus spores. Our enclosed space treatment process is rapid, providing room turnovers in under one (1) hour (start to finish).

http://altapure.com/altapure/pages/hj30i

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OTHER OZONE BASED SYSTEMS

Meditrox
http://www.steritrox.com/

Sterilization and Decontamination (PATENT)

Abstract

A method of sterilization and decontamination comprises the steps of producing a humidified environment having a relative humidity which is higher than ambient humidity; discharging ozone into the humidified environment; and then introducing an aromatic hydrocarbon into the humidified environment to preferentially react with the discharged ozone to form hydroxyl radicals. Apparatus is also provided for use with the method.

http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=7604774.PN.&OS=PN/7604774&RS=PN/7604774

http://www.airpati.com/ozonekillsmrsa.htm

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Radical
http://www.steritrox.com/

Dow Microbial Control and Steritrox, Ltd. Announce Agreement (excerpt)

"Steritrox will continue the development of its technology within medical applications using its Meditrox brand as it seeks to form a similar agreement for this important application."

http://www.dow.com/microbial/news/2012/20120928a.htm

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An Altapure based perspective on some competing technologies:

UVC, H2O2 http://altapure.com/altapure/pages/competition

PAA + H2O2 http://altapure.com/altapure/pages/why

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The good, the bad and the ugly: Updates in Infection Prevention

Dr. Daniel J. Diekema, University of Iowa Carver College of Medicine

Chapter 65, 52.24

Touchless Disinfection:

"There are significant downsides right now to these technologies including their cost, the impact they have on room turnover, the fact that they can really only be used for terminal room disinfection. So there are a lot of problems associated with them and the other problem is getting back again to the research agenda.........

http://www.dhslides2.org/mgr/mgr012513f/f.htm