This looks like a truly excellent partnership deal for Incyte. I've never seen such a good deal for a product which isn't through Phase 3 (plus a preclinical candidate thrown in). Note that Incyte is keeping all U.S. rights, all non-oncology/hematology rights (e.g. RA) and may get a total of $1.31B in upfront payment and milestones. Plus Novartis pays much of the future development costs and gives Incyte a double digit royalty on ex-U.S. sales. Pretty amazing.
It seems clear that Novartis thinks the hem-onc JAK2 inhibitor market is likely to be a lot bigger than just myelofibrosis ...
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