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OFP

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Alias Born 12/13/2011

OFP

Re: dadofmarcmax post# 121172

Thursday, 09/21/2017 12:10:55 PM

Thursday, September 21, 2017 12:10:55 PM

Post# of 458952
The obvious problem with this "tip of the iceberg" sentiment is that it is a recognition that the MOA is not known. Directly following from it is that the MOA narrative the company has been pushing including pretty much ALL their preclinical testing and claims of cellular homeostasis become moot.

Of course a compound tested without a logical MOA is really a shot in the dark. A priori probabilities are shot....with confidence in any finding reduced.
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