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Post# of 251775
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Re: Bickema post# 210279

Wednesday, 03/29/2017 4:49:21 PM

Wednesday, March 29, 2017 4:49:21 PM

Post# of 251775
Inhalers are really hard - it's tricky to get a reproducible dose. Lots of variables (particle size, amount of air, velocity, duration, etc.) determine how much drug gets to the lungs and how much end up in the mouth and throat. The originator can adjust the drug concentration to get the dose they want - they just need to be consistent, but a substitutable generic needs to match the original closely.

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