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Re: jq1234 post# 209221

Saturday, 02/18/2017 6:51:54 PM

Saturday, February 18, 2017 6:51:54 PM

Post# of 251817

Roche…stated PD-L1 expression on tumor infiltrating immune cells (IC) predicts responses to atezolizumab better than PD-L1 expression on tumor cells (TC).

BMY/MRK/AZN take the opposite side of the argument and say that either the distinction doesn’t matter or the relevance of the distinction has not been established.

This distinction dates back at least a couple of years; I first heard about it on a MRK CC in 2015, IIRC.

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