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Re: jfmcrr post# 98248

Monday, 01/16/2017 8:34:17 PM

Monday, January 16, 2017 8:34:17 PM

Post# of 428969
jfmcrr...

Quote: "More likely is that even given an identical disease process, some individuals would be more susceptable to the process and more responsive to the treatment, broadly speaking, based on genetics, single vs multiple health issues, diet, etc. Given that, might you not get a 25% RRR made up of an 8% RRR among the healthiest cohort and a 45% RRR among the most susceptable/responsive cohort? Say active non diabetic vs immobile diabetic. Again, the population for Reduce It is as noted "old and sick" and an 8% RRR among is not what we'd like to see or likely to see. But as the subgroups could make marketing targeted and an easy stroke, so could they make it problematic."

How do you come up with these conclusions? What are you...an epidemiologist, a clinician, or just some guy who likes to blow smoke rings? FYI, the RRRs could be higher in the healthier patients.. just fewer events..that would be more of a challenge to the trial. The "sick" patients will by definition have more events and a high RRR in that group is just what we need...

Stick to beating up on the English language and trying to come across as cool....Youll prolly come acrost as smarter...

":>) JL
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