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DewDiligence

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DewDiligence

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Re: biocqr post# 201969

Monday, 12/05/2016 8:22:48 PM

Monday, December 05, 2016 8:22:48 PM

Post# of 253171
AGIO -12%—shareholder lawsuits filed—on phase-2 data in pyruvate-kinase deficiency:

http://www.fool.com/investing/2016/12/05/why-agios-pharmaceuticals-inc-stock-fell-sharply-t.aspx

Updated data from DRIVE PK with additional patients and longer follow-up demonstrate that 47% of all efficacy evaluable patients (n=15/32) and 58% of evaluable patients with at least 1 missense mutation (n=15/26) treated with AG-348 experienced a maximum hemoglobin (Hb) increase from baseline of >1.0 gram per deciliter (g/dL).

These response rates are lower than the previously reported numbers for this trial (when n was smaller).

“The efficient-market hypothesis may be
the foremost piece of B.S. ever promulgated
in any area of human knowledge!”

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