Organ-On-A-Chip Startup, Emulate, Grabs $45M to Shake Up Drug Discovery http://www.forbes.com/sites/luketimmerman/2016/10/20/organ-on-a-chip-startup-emulate-grabs-45m-to-improve-drug-discovery/#42636a766e70 The big idea is that “organs-on-a-chip” may someday provide a more reasonable lab simulator for drugmakers seeking to understand how their drug candidates work, and whether they’re safe, before they go into human clinical trials. Given that only about one in 10 drug candidates that enter human tests ultimately proves safe and effective enough to win an FDA approval to become a prescription medicine, existing models leave plenty of room for improvement. Worldwide pharmaceutical R&D totaled $141 billion in 2015, according to EvaluatePharma. Even a slight improvement in the efficiency of drug discovery could be worth billions to drugmakers.