Wednesday, October 12, 2016 3:25:42 PM
DMPI DelMar Pharmaceuticals Inc.
http://www.insidermonkey.com/blog/three-cancer-plays-for-the-fourth-quarter-of-2016-478857/
This company is developing a host of different target assets, but by far the most advanced, and the one that we are interested in for the purposes of this discussion, is a brain cancer target called VAL-083. It is a chemotherapy agent, but not in the traditional sense. At least, that is, its mechanism of action differs from standard chemotherapy agents, and it’s this difference that makes it interesting.
The drug is able to form DNA cross-links in tumor cells, and then halt progression of the cell’s replication process at what is called the S phase – the phase at which the DNA in the cell is copied before division. This is fatal for tumor cells, but not for healthy cells (at least not to a particularly high degree). The upside of this is that the drug can be used to target cancers while minimizing toxicity, and in turn, the side effects associated with traditional chemotherapy agents.
60 minute
Daily
DMPI DelMar Pharmaceuticals Inc. brain cancer
http://www.insidermonkey.com/blog/three-cancer-plays-for-the-fourth-quarter-of-2016-478857/
This company is developing a host of different target assets, but by far the most advanced, and the one that we are interested in for the purposes of this discussion, is a brain cancer target called VAL-083. It is a chemotherapy agent, but not in the traditional sense. At least, that is, its mechanism of action differs from standard chemotherapy agents, and it’s this difference that makes it interesting.
The drug is able to form DNA cross-links in tumor cells, and then halt progression of the cell’s replication process at what is called the S phase – the phase at which the DNA in the cell is copied before division. This is fatal for tumor cells, but not for healthy cells (at least not to a particularly high degree). The upside of this is that the drug can be used to target cancers while minimizing toxicity, and in turn, the side effects associated with traditional chemotherapy agents.
60 minute
Daily
DMPI DelMar Pharmaceuticals Inc. brain cancer
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