Avid Bioservices Inc (CDMO)

[cjgaddy]

realist, did you get your “49% pts. censored” line that you've been relishing in recently from carboat? The reason I ask is, it's wrong, and way wrong. The correct answer is 32%.

Just so you know, patients are censored from the K-M Survival graph not only if they are lost to the study, but also if THEY ARE STILL ALIVE at the time that the trial was unblinded. These were the Ph2 trial's Final Results, and the protocol required the trial to be stopped when 68% of the patients died. All of the remaining patients must be (and were) 'censored' (ie, are not put in the K-M Survival Graph).

6-3-13/ASCO’13: Final Data Ph.II 2L/NSCLC http://tinyurl.com/my8qxw7
…60% improvement in MOS: Bavi/3mg=11.7mos. vs. 7.3mos. for CTL-arm(combined Bavi/1mg + DoxyOnly arms), HR=.662, P=.113

32% (39) of the 121 pts were censored in the K-M Survival Curve...



= = = = = = = = = = = = = = =
Censoring the Data
“Mathematically removing a patient from the curve at the end of their follow-up time is called "censoring" the patient. This is perhaps an unfortunate choice of words, but you should understand that in this context "censor" is a purely technical term and has nothing to do trying to limit information or prevent expression. The aim is to produce the most accurate possible survival curve taking into account all the of information available. A few conspiracy minded alternative therapy advocates accuse conventional medicine of "censoring their data", presumably to conceal something - if you ever see this argument, one thing you can conclude for sure is that the writer is totally clueless!”
FROM: http://cancerguide.org/scurve_km.html