InvestorsHub Logo

realist1

10/12/15 10:45 PM

#238593 RE: cjgaddy #238587

RE "realist, did you get your “49% pts. censored” line that you've been relishing in recently from carboat? "

No, I got it from this article:

http://www.thestreet.com/story/11720253/2/peregrine-pharma-cash-crisis-and-exaggerated-survival-benefit.html

"Seventy-nine patients were enrolled in the two bavituximab arms but only 40 patients were accounted for in the survival analysis. That means 39 bavituximab patients, or 49%, were censored and excluded from the analysis."

BTW, I do not "relish" a statistic.

You say 32%, the article says 49%. I guess the 49% turned into 32% between the unblinding and the final results?

CuresForHumanity

10/13/15 8:29 AM

#238612 RE: cjgaddy #238587

CJ thank you so much for explaining this. I didn't realize that patients were censored if they were still alive when the 68% of events occurred. So, the fact that 50% of bavi patients were censored; whereas, the control arm had only 25% censored - is a fantastic thing! I was also surprised by how great the results were for the healthier arm. These numbers beat the opdivo healthier arm in their phase iii published if I remember correctly. I'm assuming that the two numbers in the overall survival were split out between the two levels of ECOG is that correct?