Sunday, April 19, 2015 10:11:02 AM
I wonder if this is why we see the trend and paradigm shift towards Immuno-Oncology and the fact that inflammation leads to higher levels of MDSC's, which naturally leads to higher death rates. Only lower levels of MDSC's have been proven to be associated with an optimal immune response. I must sound like a broken record at times, but Dmitry Gabrilovich (Peregrine KOL) has suspected/known/proven this many times up to this time and is the reason why he is with Peregrine Pharmaceuticals.
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Oh.... I forget to clearly point out that inflammation is tied to higher levels of MDSC's as well...
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"Bavituximab is a first-in-class phosphatidylserine (PS)-targeting monoclonal antibody that is the cornerstone of a broad clinical
pipeline." -- Big Pharmas nightmare... unless they are fortunate enough to have The Bavi Edge!
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