NanoViricides Inc. (NNVC)

[Steady_T]

If you read through the slides and discussion that were posted about Ebola entry into cells, you might have noticed that the structure that binds to the NPC1 has a glycan cap on it while circulating in the blood.

As I understand the infection process the cap is removed by the cell in the initial stages of the binding process. Subsequent steps involve the NPC1 site for entry through the cell wall. But, that is after the virus has already been surrounded in the micropinocytosis step. At that point it is protected from the Ebolacide.

Therefore a ligand that binds to NPC1 inverse structure won't have anything to bind to on the virus while it is circulating in the blood. That glycan cap is in the way.




"Notice the glycan “caps" on the attachment protein on the surface of the virus (virus in red)"

From you post by Dr. Seymour.
http://investorshub.advfn.com/boards/read_msg.aspx?message_id=106254801