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Re: jq1234 post# 181547

Friday, 08/29/2014 6:23:25 PM

Friday, August 29, 2014 6:23:25 PM

Post# of 251620
>>viraemia load at time of treatment more important than days in general

We are looking at a seriously logarithmic viraemia curve for this infection. Doubling time on average looks to be under a day, so the half-dose vs. full-dose would correspond in general to about a day's delay or less. (But there isn't enough data to know this for sure - could be that it's slower at the beginning with a smaller dose).

But there does seem to be a fair amount of variablity, and so you are correct that "days" aren't a good measure. Could easily be 3 logs difference on the same day.

Peter

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