Wednesday, August 27, 2014 2:35:47 PM
I did read that and remember it, but was confused because it seems the author was saying they would have multiple ligands (the one they used before, plus an "extra" one) on the same nanomicelle, which I thought was not possible.
So instead of "adding an extra viral receptor," they are creating a new ligand for a new version of the EbolaCide, apparently, based on NPC1 receptor. (Unless my understanding is incorrect about how many different ligands can be attached to a nanomicelle).
Leif, good question about whether it is required that multiple viral surface proteins need to be bound by multiple smaller nanoviricides to completely encapsulate the virus in order to destroy it. Maybe it only takes one or a few nanoviricides to tear open the viral envelope to render it "dead," and it isn't required to cover the entire virus.
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