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Wednesday, 08/27/2014 1:22:47 PM

Wednesday, August 27, 2014 1:22:47 PM

Post# of 146196
I was wondering what approach Diwan would take and here it is spelled out!! Got to start paying attention to posted articles!

Happy days ahead - Ebola has met its match! Attack the Ebola decoy, then zap the Ebola virus - game over.

Ref:

At this facility Diwan hopes he’ll eventually be able to manufacture a drug that can defeat Ebola. Shortly after Diwan was approached about Ebola in 2005, interest and funding for research dried up and NanoViricides Inc. shelved research on an Ebola drug. But when the current Ebola outbreak began and showed no signs of slowing down, the company decided to restart research on that drug.

Today, Diwan believes he’s come up with a way to overcome the virus’ decoy. Step one will be adding an extra viral receptor mimicking ligand to the nanoviricides designed to overcome the virus’ decoy, and step two will be upping the dosage of the drug—because the drug’s toxicity is so low there’s no danger in doing this and the increased dosage will help make treatment effective even if some nanoviricides are taken up in defeating the decoy.

Diwan believes this drug could be more effective than any of the experimental Ebola drugs currently being sent to the region. And unlike those drugs, Diwan’s drug is not expected to have adverse side effects. Plus, his company has the capability at its Shelton facility to produce it in great enough numbers to handle an outbreak. More importantly, because the nanoviiricide is “broad-spectrum” drug, it is expected to work against all versions of Ebola, unlike the other experimental drugs.

The only problem is the concept for the Ebola nanoviricides can’t be tested readily. Diwan’s company conducts all animal and live-disease testing offsite. With Ebola this becomes complicated. There are only a handful of labs in the world with active strains of the virus, and these labs are currently overwhelmed because of the outbreak.

When Ebola is brought under control, or possibly if it continues to spiral out of control and the world gets desperate, Diwan’s drug will be tested. NanoViricides has connected with the US Army Medical Research Institute for Infectious Diseases (USAMRIID) as well as the National Institutes of Health facility (both in Maryland), and they are working out a plan for Ebola drug testing. If the drug is successful, manufacturing could begin in Connecticut.


If that day ever comes, Diwan believes the horrifying Ebola virus will be destroyed, and the Connecticut Company’s motto, “Bind, Encapsulate, Destroy” will ring true. http://www.connecticutmag.com/Blog/Connecticut-Today/August-2014/Anti-Ebola-Drug-Under-Development-by-Connecticut-Company/?cparticle=4&siarticle=3




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