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Anavex Life Sciences Corp (AVXL)

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Last Post: 10/20/2017 1:02:04 AM - Followers: 716 - Board type: Free - Posts Today: 4

Anavex Life Sciences Corp (AVXL)

Company website:
Company Address:
51 West 52nd Street, 7th floor
New York, NY
10019 USA

CIK:  0001314052

Anavex®Life Sciences Corp. (the “Company”) is a clinical stage biopharmaceutical company engaged in the development of differentiated therapeutics for the treatment of neurodegenerative and neurodevelopmental diseases including drug candidates to treat Alzheimer’s disease, other central nervous system (“CNS”) diseases, pain and various types of cancer.  The Company’s lead compound ANAVEX®2-73 is being developed to treat Alzheimer’s disease, Parkinson’s disease and potentially other central nervous system diseases, including rare diseases, such as Rett syndrome.

Anavex®Life Sciences’ lead drug candidate, ANAVEX®2-73, recently completed successfully a Phase 2a clinical trial for Alzheimer’s disease.  ANAVEX®2-73 is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors.  Preclinical studies demonstrated its potential to halt and/or reverse the course of Alzheimer’s disease. It has also exhibited anticonvulsant, anti-amnesic, neuroprotective and anti-depressant properties in animal models, indicating its potential to treat additional CNS disorders, including epilepsy and others.  The Michael J. Fox Foundation for Parkinson’s Research has awarded Anavex® a research grant to develop ANAVEX®2-73 for the treatment of Parkinson’s disease to fully fund a preclinical study, which could justify moving ANAVEX®2-73 into a Parkinson’s disease clinical trial.  ANAVEX®3-71, also targeting sigma-1 and M1 muscarinic receptors, is a promising preclinical drug candidate demonstrating disease modifications against the major Alzheimer’s hallmarks in transgenic (3xTg-AD) mice, including cognitive deficits, amyloid and tau pathologies, and also with beneficial effects on neuroinflammation and mitochondrial dysfunctions.

The Company is in preparation for ANAVEX®2-73 for a Phase 2/3, placebo-controlled trial in Alzheimer’s disease as well as a Phase 2, placebo-controlled trial in Rett syndrome, for which the U.S. Food and Drug Administration (FDA) granted Orphan Drug Designation (ODD) for ANAVEX®2-73 and a Phase 2, placebo-controlled trial in Parkinson’s disease.

Headquartered in New York, Anavex® Life Sciences is an American publicly traded corporation on Nasdaq quoted as AVXL


Patent Info:

Clinical Trials:
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Company News Releases:
Share Structure:  See SEC filings
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AVXL News: Statement of Changes in Beneficial Ownership (4) 10/19/2017 06:47:52 PM
AVXL News: Statement of Changes in Beneficial Ownership (4) 10/18/2017 09:47:41 AM
AVXL News: Statement of Changes in Beneficial Ownership (4) 10/16/2017 11:07:52 AM
AVXL News: Anavex Life Sciences Reports PK and PD Data from Phase 2a Trial of ANAVEX®2-73 in Mild-to-Moderate Alzheimer’s Disease Pat... 10/12/2017 07:00:00 AM
AVXL News: Current Report Filing (8-k) 10/06/2017 05:18:01 PM
News News Alert: Statement of Changes in Beneficial Ownership (4) 10/19/2017 06:47:52 PM
#125420  Sticky Note Our company may be finally gaining traction as polarbear77 10/19/17 05:05:36 PM
#123787  Sticky Note KEM != Stats MycroftHolmes 10/10/17 05:39:36 AM
#116985  Sticky Note Anavex Life Sciences Corp. - Things To Know. nobrainerstocks 08/24/17 06:32:49 AM
#103034  Sticky Note To answer your good questions. falconer66a 04/26/17 10:18:09 AM
#125465   my bad it should be goooooood morning vietnam longtermbeliever 10/20/17 01:02:04 AM
#125464   from vietnam..goooood morning loooooongs and goooood morning vietnam.hold longtermbeliever 10/20/17 12:53:48 AM
#125463   Days and weeks ahead will be quite meaningful. bennyboy1 10/20/17 12:44:19 AM
#125462   Great post Polar.. what's each worth..5%? 10% We McMagyar 10/20/17 12:01:51 AM
#125461   Thanks, I think the recent take down was XenaLives 10/19/17 11:05:44 PM
#125460   Xena, I Took all filings from 08012017 and Rubyred77 10/19/17 10:49:27 PM
#125459   I have seen no evidence of "large institutional sells"... XenaLives 10/19/17 09:49:18 PM
#125458   kevin---agree--nice list--will be following closely--long Avxl ! plexrec 10/19/17 09:14:19 PM
#125457   XBI was made to rally in 2017.. 123tom 10/19/17 08:53:35 PM
#125456   Re: Sigma & CRISPR MycroftHolmes 10/19/17 08:52:04 PM
#125455   attila, another significant point of those awards is powerwalker 10/19/17 08:36:02 PM
#125454   I wonder if it has that tailwind.... 123tom 10/19/17 08:23:35 PM
#125453   And a huge swing and a miss. Maybe Batermere 10/19/17 08:19:21 PM
#125452   WHO did all the buying today Pineapple1 10/19/17 08:11:32 PM
#125451   We are starting off this quarter with large SquealingSquid 10/19/17 08:09:57 PM
#125450   I don't recall. What was the reason? attilathehunt 10/19/17 08:06:04 PM
#125449   I bet the buyers were those crazy non-technical kevindenver 10/19/17 08:03:12 PM
#125448   great writeup Polar! attilathehunt 10/19/17 07:57:42 PM
#125447   Now AVXL might be getting somewhere. 123tom 10/19/17 07:56:05 PM
#125446   kevin-Millstone--thanks--good explanations--I get it-was not quite sure--know be plexrec 10/19/17 07:53:46 PM
#125445   Good question that's where 10b5-1 trading plan rules kevindenver 10/19/17 07:47:44 PM
#125444   Nidan - Would love to see Dr.M. execute attilathehunt 10/19/17 07:46:38 PM
#125443   The purchases are according to an SEC sanctioned Millstone 10/19/17 07:42:10 PM
#125441   And bought at 3:15 close to the attilathehunt 10/19/17 07:29:20 PM
#125440   Maybe the signal is for all the naysayers... Penny Double 10/19/17 07:18:31 PM
#125439   Sorry if I sound naive--but I didn't think plexrec 10/19/17 07:15:21 PM
#125438   It's been three years.. Total miscalculation of the intelligence McMagyar 10/19/17 07:12:18 PM
#125437   I'd say he is confident one of those ven69 10/19/17 07:02:20 PM
#125435   I say he keeps buying until we get neiu 10/19/17 07:01:05 PM
#125434   Missling bought another 375 today ven69 10/19/17 06:56:51 PM
#125433   It would be nice to hear something about SquealingSquid 10/19/17 06:55:08 PM
#125432   Its public why he got awards. mrplmer 10/19/17 06:54:37 PM
#125431   Jon - I hope Missling is playing hardball. attilathehunt 10/19/17 06:49:55 PM
#125430   McM - I honestly believe once big dollar attilathehunt 10/19/17 06:39:03 PM
#125429   FWIW - Biogen releases 3rd quarter earnings on powerwalker 10/19/17 06:22:49 PM
#125428   Sticky deserving post !!!! Great post polar--as plexrec 10/19/17 06:10:02 PM
#125427   From a Stones lover: One of their earliest xodcode 10/19/17 06:01:14 PM
#125426   LOL! basparks79 10/19/17 05:57:50 PM
#125425   Ti i i i i me is on McMagyar 10/19/17 05:50:41 PM
#125424   Time is rarely on your side.. It's good to McMagyar 10/19/17 05:46:15 PM
#125423   Attila...Excellent connect the dots posting. The really good nidan7500 10/19/17 05:31:00 PM
#125422   and, * Axon Enterprise: Working With SEC to Discuss Investor2014 10/19/17 05:29:56 PM
#125421   Missling decided to buy 750 shares/week for at attilathehunt 10/19/17 05:13:48 PM
#125420   Our company may be finally gaining traction as polarbear77 10/19/17 05:05:36 PM
#125419   What a mess. Investor2014 10/19/17 04:52:40 PM
#125418   Wishful thinking I know... RajeshBoomi 10/19/17 04:51:30 PM
#125417   Don't go out on a limb. poonch1ne 10/19/17 04:46:37 PM
#125416   Thinking 5+ by eoy RajeshBoomi 10/19/17 04:43:59 PM
#125415   jinxed it - my bad. poonch1ne 10/19/17 04:39:46 PM
#125414   Closes at the HOD----4.70....bodes well I would think---someone plexrec 10/19/17 04:33:48 PM