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New Tweet,
Shareholder Update !!!
@ADHCMANAGEMENT $ADHC
— ADHC MANAGEMENT $ADHC (@ADHCMANAGEMENT) September 13, 2024
Shareholder Update !!!
Year end filing for period ending 7-31-24 is expected to be submitted soon. Share reduction, Debt Reduction & Non Dilution LOCK UP! to be updated in Q1 filing. More Corporate dev are in place will be publicized in the near term.
I haven’t been following closely lately here, but I am guessing it is because this is an area of need and one that matches previous research, with other ccr5 trials and papers. I am guessing they suspect that is the fastest way to approval, because with good results the time to approval can be greatly shortened compared to those cancers with good results already. Also they have a good way to show the drug is working with measuring crcs directly as direct evidence is needed for fast approval.
Example:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407580/
“CCR5 expression was found to increase with primary tumor size and peaks in T4 CRC tumors (metastatic colon cancer). In liver metastases, CCR5 intensity increased, compared to primary tumors, but the stain was detected in small isolated areas (patchy staining). Low CCR5 expression in metastases was found to characterize patients with prolonged disease-free survival and disease-specific survival. Patchy CCR5 expression in cancer cells is a signature of liver metastases, and maraviroc was still effective in patients with CCR5 “patchiness”.
The C-C chemokine receptor type 5 (CCR5) plays a role in colorectal cancer (CRC) progression and is associated with several factors, including:
Tumor size
CCR5 expression increases with tumor size, and peaks in T4 CRC tumors, which are metastatic colon cancer.
CCR5 expression increases in liver metastases compared to primary tumors, but is detected in small, isolated areas.
Disease-free survival
Low CCR5 expression in metastases is associated with prolonged disease-free survival and disease-specific survival.
Tumor microenvironment
CCR5 signaling increases the infiltration of regulatory T-cells and myeloid-derived suppressor cells into the tumor microenvironment. This can contribute to cancer survival and progression, and may make tumors resistant to immunotherapy.
Macrophage repolarization
CCR5 is a potent regulator of macrophage repolarization. It promotes a proinflammatory, prometastatic phenotype of tumor cells.
Mesenchymal stem cells (MSCs)
MSCs produce large quantities of CCR5, and the CCL3/4/5-CCR5 axis promotes tumor progression.
Looks like it is getting ready to run
21c, crazy move.
OTCN has been gone for a couple days now I believe, at least when I have checked Looks like whatever leftover lingering dilution from before is gone now. Just need it to pop over 30 for launch.
Looking good today. When these charts starts a continued uptrend, I like adding on the 8 day pullback, which it did yesterday. They normally pull back to that point with support. Nice move back up day.
Nice, updates coming. I'm interesting in seeing where that 140M share reduction comes from. With the debt deal, I am thinking they worked out some deal with Ernest for debt plus his shares. From the last filing, he seems to be the only one with that many shares to reduce, unless they got the shares from multiple sources.
Tough day for the market in general, SPY and Dow are bringing everything down with them today.
Funniest thing, people on Twitter worried about ADHC are mostly in HIRU, which just maxed out their OS, which is necessary a bad thing. Just worry about yourself is all I'm saying. I don't go there posting as I don't follow it. They just added more shares last week than the entire OS of ADHC, without the 142M share reduction coming.
Top volume August 29th under 1c vs float. There is only one other ticker under 1B float and this is without the OS update coming, which should put the OS under 1B. This can really move if it breaks over 30.
Symbol Price Vol OS Float
PSRU 0.0001 468716915 12.7B 11.8B
ASII 0.0011 361689105 2.5B 1.8B
SPQS 0.0004 89969132 2.8B 2.1B
SWRM 0.0003 87619193 1.9B 1.9B
IDVV 0.0007 77214785 1.5B 1.2B
HMBL 0.0003 59150244 19B 17B
HIRU 0.0043 54540054 3.9B 2.7B
LTNC 0.0017 39733731 15.4B 9.6B
NBRI 0.0008 37384300 7.3B 5B
AITX 0.0032 36990297 11.6B 11.6B
ABQQ 0.0006 36727242 2.3B 2.3B
BIEL 0.00035 34705890 25B 24B
GSAC 0.00035 31020000 2.9B 1.2B
PSYC 0.0003 28634210 1.0B 900M
ADHC 0.0021 28070723 1.2B 851M
NP can’t handle a candle to RP. Everyone knows how bad NP was now, but RP still has some people blinded, while at the same time professing enlightened. Amazing really. A simple google search when he first was announced would have done it. It has been washed clean now though by the man himself. It probably on the hidden web behind a firewall somewhere still though.
$LDSN, back to 2c, big vol come back this morning knocking out the ask on 2s. I grabbed a few to see if it get a cat bounce after the run to $1
It is slow for me too, small cap and otc moving very slow for me. I came here just to check if anyone had anything moving I didn't see.
$LDSN, opened 27c, back to 9c, now 15c
$LDSN, from 95c back to 8c in last two hours. I grabbed some 8s. Just a crazy stock.
If you are going to make condescending remarks, especially those including intelligence—at least keep up with the conversation. The first comment about CYDY implies you are not.
Reminds me of a Gervais quote,
“When you are dead, you do not know you are dead. It's only painful & difficult for others. The same applies when you are stupid.”
$GGEI, took a month but tripled today...
I went back and looked at volume in 21, here is a chart with OTC in billions, for reference last month OTC pulled in 45B, it will be interesting to see what May is. And the second is a 5 year chart for IWM, a ETF for Russell 2000 small cap, which to me looks to have been consolidating since 2022 and now is testing the top of the range of that sideway movement for 2.5 years. If we get a breakout and move like 2020-2021, I am guessing, it would bring back the volume and maybe the market is anticipating that happening right now with these supernova spikes in small caps. Just some opinions...
[quoteThe real question is whether or not we'll see a reputable partner step in, per Jay's comments. That would be the big][/quote]
Agreed, you have to see something substantial like that to see a continued share price increase beyond riding the current small cap stock upward trend-- that only takes you so far.
But, the liquidity issue has peeked my interest, this is by best month since 2021, so I will research it a little when I have time this week. Covid played a big role, but also the bull market spread out from large caps to small caps, and the small cap bull hit 2021. Small caps haven't done as well since then compared to large caps, interest rates a factor many think. We could be seeing a similar bull spread out to small caps now. But numbers are needed. I just checked and and last month OTC did $45B in dollar volume, up 50% from the $30B April 2023, link below. Not surprising I made 50% more last month than April 2023 trading, liquidity = money in my case. That number is climbing, but I don't have the 2021 numbers to compare. It would be interesting to see a 2021-2024 monthly $ volume chart for all OTC. Then we can visually see what is happening, and how that trend is progressing, and maybe help people make a little money for those paying attention to the trend if indeed we are at the start of a small cap bull run or middle etc.
https://otce.finra.org/otce/marketStatistics
You might be correct. Volume in OTC comes and goes in cycles, the 01 was the biggest spike from all the Covid money and people with free time. This is my biggest week since 01 trading. Hopefully this wave is just started and continues for some time, as people make money, they roll it over in other stock in the FOMO mania going on right now.
Stocks under 20c with premarket volume over 100k ranked highest to lowest
$PEGY, $SINT, $NBY, $SLNA, $SCPX, $CYN, $AGRI, $VHAI, $BSFC, $KTRA, $HLTH, $ASTI, $SMX, $VERB, $BURU, $KITT, $CEI, $BIOL, $OBLG, $SVMH, $PRST
After the AMC and GME run this week that Zach Morris started two weeks ago, that Roaring Kitty ignited by liking his post, after his discord group loaded . They are running small cap tickers, anything under 10c ran, like FFIE 4c to $2. Or CRKN or KXIN or AKAN or GWAV running right now, etc. if this plays out like 2021, they will start running OTC tickers next, trips, then pennies, etc. I remember back in 2021, there wasn’t a single nasdaq small cap under $1, because they ran them all. No trip OTC, etc. Anyway, to be short any ticker right now before we see how this plays out is dangerous imo.
Just saying…
It will very likely be a NT 10K with the SECs blessing since they banned their audit team right before it is due. Think people, goodness.
$ILST .0027s, RDGL .23s
That stinks. I was wondering what happened with stockcharts and ihub. I post live charts just so I can go back and pull up the post to see how it is going. It will be nice to just look at the IBOX. I didn't realize you were in this. I don't read the boards as much as I should. A Lot of people here I follow I noticed though as I have read a little, which makes it an interesting one for me.