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It would seem that somebody must be paying him to speak out and comment on NWBO. This is a direct quote from him when asked to comment by a newspaper about his life after prison.
“When contacted by phone, Shkreli said: “I will only comment if you give me significant financial compensation.””
Therefore, IT WOULD BE CONSISTENT WITH That statement, THAT SOMEONE must be giving him significant financial compensation to trash NWBO. That makes sense.
Thanks, Doc. I just seem to recall that when you get an immune response, sometimes the tumors can actually radiographically appear larger because of all the immune cells congregating in the area of the tumor. It’s not a bad thing, but it might be kind of hard to judge size Radiographically. My worry is that we get into another trial that we can’t interpret very easily. if we just use size criteria. We have to carefully look at size maybe on sequential radiographs so that we count for those tumors that look like they have grown when in fact, they just have a good immune response.
I don’t get this. Wasn’t this the whole problem with pseudo progression? And PFS survival? That the size of the tumor or area of enhancement did not correlate with overall survival so why now are they going back to going with tumor size? Is she talking about tumor sites outside the brain?
Very good advice for anybody who speaks truth and happens to live in Russia.
Thanks, gotcha. I thought when learning said gifting that he was saying that NWBO was just giving the shares to him. He always, and the family has to pay the exercise price, which does give money to the company, which is what I want. Because the company needs funding.
I didn’t realize that Bosch was gifting them to his family. This makes smart sense so now his family won’t have to report i.e. the family won’t have to report trading.
It looks as though maybe he’s preparing for the stock price to appreciate rapidly and may want to take advantage of that I don’t know. That’s what it seems.
Learning? These weren’t total gifts. I believe they had a price on them like $.30 or something like that or maybe $.20 that he has to pay. They weren’t totally free. I think they were warrants weren’t they? So anyway it’s a buy an insider. Correct?
“Pullback”??????
Yep, Yep, agree, they can’t say anything now… Unless they’re on the big Biz show!
Brazen just to give you some historical reference. Temezolamide TMZ is a chemo that was given with radiation in this disease and well over a decade ago almost 20 years ago a guy by the name of Dr Stupp published his results in the New England Journal medicine where they added this TMZ chemo to radiation and it I think increase the median survival, just over a month or a month and a half or some minimal thing like that.
But the thing is nothing has worked for this type of cancer previously and so even a month or two medium survival increase was statistically significant and clinically significant for patients. And TMZ became immediately the new standard of care. It is a multi billion dollar pharmaceutical.
After that was published. I think you should review what senti says regarding the survival tail. That’s where survival is happening not to everyone, but certainly a substantial minority that would otherwise succumb to this terrible disease.
Nemo
Just a word of advice. At the end of all of your posts just put IMO. AND THAT SHOULD COVER YOUR BS. AS YOU KNOW, IMO STANDS FOR IN MY OPINION.
AS YOU WRITE YOUR POST, YOU WRITE THEM AS FACTS. NOT OPINIONS. THAT CAN GET YOU INTO TROUBLE JUST SOME FRIENDLY ADVICE.
Here’s the draft version of the next NWBO, communication from the investor relations department. You’re the first to see this!
In the realm of health, I hold great promise,
A vaccine crafted, with science to harness.
Using your own cells, I aim to restore,
With minimal side effects, I’m worth waiting for.
Regulatory paths, so lengthy and slow,
The study stretched on, like a river's flow.
In the fall I may shine, but the wait is unsure,
When will the shareholders see their cure?
What am I?
Here’s what he says.
I oversee the process, both near and far,
Preparing for checks, I’m the guiding star.
In the UK and US, I pave the way,
For inspections to come, I lead the fray.
What am I, with plans that must align,
Ensuring all’s ready, each detail's divine?
What am I?
Sorry, I miss spoke. Dang it. It’s obviously a quadruple bottom, dangling, teapot handle, Navid sell, elephant, foot, chart pattern.
Yeah, it’s a quadruple double bottom teapot lid, elephant, foot chart pattern.
Navid sold…..AGAIN!
The only positive that I can see with this development is that at least someone on the board of directors is feeling our, retail, Pain with liquidity issues and low stock price.
Maybe during their insider discussions, he can raise a voice in support of doing things that increase share price and increase liquidity, and perhaps a liquidity event for long suffering retail like us.
Because it definitely seems that LP does not have this even a little bit on her radar. At least having one of her insiders having a painful liquidity need might help her realize a little more fully that we don’t have an eternity to get things done with this therapy. It does seem at times, that management has no concept of the finite nature of humans but carry’s on like there’s absolutely no rush ever and we have infinite time, and that humans are immortal
At least with Navid needing to do this, for whatever reason, maybe our needs for a liquidity event at some point in time will have an increase acknowledgment in the boardroom.
Bottom line is invest now, this is way undervalued and this is a multi bagger in the near term future. Try to spin that. This baby is not going bankrupt. They have valuable patents on a valuable technology and are on the cusp of approval in an important market.
Yeah, I thought so, you can’t spin what I said negative.
Actually, I am one of the lucky ones who have purchased a few years back at between $.14 and $.22. Averaged down, then made a lot of money on the last big rise and then sold some but now I’ve reloaded totally and more than totally.
Also, in the years that this was optionable, one could make a lot of option money from the shorts, especially right before Woodford came in. A lot of the shorts took a bath a bad bath then. And I made a lot on that. A ton.
I can’t wait for it to get up listed so that I can do the option thing again. Mitigate risk. As much as possible.
Find it yourself and don’t be lazy.
There’s a cadre of posters, yourself included, who only say negative things about the company are totally one-sided and never report on anything positive. Furthermore, they spend anything that is remotely positive to a negative tilt.
At least I am a true investor, and I post positives and negatives. Like I was really pissed off that Navid sold right before we submitted and I made my feelings known.
But I have followed this company for nearly 15 years now and I’ve been invested all of that time. I have met the executives at meetings and I have found them to be honorable.
I have an enormous long position in this stock over many years.
Linda is doing this primarily out of a sense of honor in memory of her father who died of glioblastoma. Yes, she gets paid, but who doesn’t for working their ass off and taking a bunch of verbal abuse from the likes of posters, such as yourself.
Bottom line is invest now, this is way undervalued and this is a multi bagger in the near term future. Try to spin that. This baby is not going bankrupt. They have valuable patents on a valuable technology and are on the cusp of approval in an important market.
Spin that negative, please. Just try to do it.
And from reading this board, there appears to be a lot of actors who are willing to pay to have bad intentions towards NWBO, for example, there are a number of posters only site spouting negative things totally 100% of the time. Now that is weird and they must have some incentive for doing that. Just saying look at reality.
Given that reality, the company has to be extremely careful.
As I recall, Smith did address that and said that it was a positive thing for NWBO to have close relationships with the manufacturing entity. Gave NWBO more control less chance of being subverted by actors who do not have the best intentions. So what’s your point?
Learning, why do you say that? I know his history. I know he worked in the industry, know he had some regulatory issues along time ago, but, I also have read his well written reports and they make sense to me so because of that I’m stupid, is that what you’re saying? You are so arrogant.
I worry if we get to that point, the singular only warehouse storing all of the discoverable data will inexplicably start on fire and burn to the ground, like what happened years ago with the large Td Ameritrade warehouse. I worry these guys already criminals, can hide discoverable dataand destroy discoverable data. I wouldn’t put anything past them on this.
Thanks makes sense. Given their investment history however a short flip is generally usually something they don’t do. And I’m not sure if they have a lot of short positions. So time will tell. Thanks for your thoughts. Even though I don’t always agree with what you say, as you do have a very continuous glass half empty negative approach, I do appreciate some of the points you do raise.
So theory, you are also saying that the recent $8 million investment by a healthcare hedge fund is illegitimate?? When I look at these guys website, they have profound knowledge of biotech and the healthcare fields. Why the heck would they invest in this if it was so bad? Please advise your thinking.
So theory are you saying that Smith is not a legit analyst?
It wasn’t Dr. Ashkan who misdiagnosed. If there was a misdiagnosis, it’s usually with the Pathology.
Having worked with one of the worlds pre-eminent neuropathologist, in the past on several projects, sometimes it gets very dicey making the diagnosis. It’s easier nowadays with all of the stains, but it sounds like if there was a misdiagnosis it may have been a pathologic misdiagnosis.
I have seen that happen, several times in the past . And even have had several times where people got treated like a GBM and then on pathologic review later on a different diagnosis was made.
So this is not outside of the realm of what can and does sometimes happen. Of course it’s not good, and one always tries to avoid these sort of misdiagnosis, but they sometimes do happen.
And in a way it’s a very positive diagnosis because of the prognosis being different between different histologic entities in this space.
Just my two cents.
Agree go to Fidelity. I had other similar problems with Schwab.
Very nice Review. Yes I agree with everything you said. They need to have incentives but not at these inflated, obscenely inflated share levels; millions and millions and millions and millions of shares. This was done when the stock price was like $.17; and very manipulated.
I say vote no and let’s do a do over on compensation. Give them good compensation, but not like this. This is just wrong.
BB. Navid sold.
Wow impressive people.
Marty if I’m not mistaken, they have to pay for their warrants. Some of them have to pay up to $.35 a share. So they’re not free they’re just discounted.
My biggest problem is the number. Like millions and millions and millions of them I just can’t get my head around who would approve that many shares For somebody even if they are working their ass off. Millions and millions and millions and millions? That seems very unreasonable.
I think they’re owed some but how the hell they came up with many many many millions I will never know and cannot understand.
When you add up LP total it’s going to be like 11-12% of the entire company. Or something like 180 total million shares. Even with the dilution that is unbelievable. And they calculated all of these options back when the share price was like $.17-$.20 that’s what I think is unfair.
Or better yet, maybe Kenny will true up all of our shares!
I want management to true up my shares!
And has bozo Les worth 28 million of these warrants or something like that? I think not.
Yes, I agree. It’s a vote no for me. It’s just when I look at the numbers they are so enormous.
I know Linda is very knowledgeable and very valuable and has indeed saved the company but she does make $1 million a year and that’s a lot of money; but you look at these option warrants and I added them all up and it was something like 150 million shares or about 10% of the company. Doesn’t look like as much at these price levels but if we get any appreciation literally it’s $1 billion stock option award. Kind of like Musk.
So in the end, I think that’s a little much quite a little too much. I did like that. There was a price on them that they weren’t free. I just don’t like how many they’re getting. I think they’re do some however it’s just who decided that it was this enormous number?
Flipper, please forget about anything that Les has said or will say or has said in the past. I don’t think he’s ever said anything that has been accurate in the history of this company. I think it was his quote in 2019 that we were on the one yard lineor something like that.
He has been inaccurate continually and consistently. It’s really the only consistency with NWBO is that Les will be inaccurate in what he says always. He will never be clear. He always speaks like it’s cloak and dagger. I don’t know if he does this on purpose or if he’s just stupid. I’m kind of inclining that he’s stupid, on that side of things but a good friend of LP and loyal so she keeps him around.
He screwed up so many things with this company by not filing for different regulatory filings that are necessary, etc. etc. so my advice to you is to go with what is said in the SEC documents as those are pretty much always accurate.
Discount like 100% whatever less says. He has no credibility whatsoever.
I know I know. Thanks. But it’s tough to watch. I guess the moral of the story is to sell when Navid sells!
Note to self be very cautious when investing in any company that is suing all of its market makers.! Man there is absolutely no strength in this.
Yep Schwab kind of sucks. They pay paultry and then they do these kind of things. . Stick with Fidelity in my opinion.
From chat, GPT
The FDA defines a rare disease as a condition that affects fewer than 200,000 people in the United States, or about 1 in 1,500 individuals. This definition may vary in other countries.
As for glioblastoma multiforme, it is not considered a rare diagnosis. Glioblastoma multiforme is an aggressive type of brain cancer that accounts for the majority of malignant brain tumors. While it is a serious and relatively uncommon condition, it does not meet the criteria for a rare disease according to the FDA definition.
OK, just wondering why glioblastoma multiforme is not considered a rare diagnosis when there’s only around 35,000 diagnosed in the US per year?
I apologize for the confusion. While glioblastoma multiforme is a relatively rare form of cancer, it is not classified as a rare disease according to the FDA definition. The FDA's criteria for rare diseases is based on the prevalence of the condition in the entire population, rather than the number of new cases diagnosed each year. Glioblastoma multiforme may have a lower incidence compared to more common cancers, but it does not meet the specific threshold set by the FDA to be classified as a rare disease.