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Calmare Therapeutics Inc. (CTTC)

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Last Post: 5/25/2016 9:43:03 AM - Followers: 38 - Board type: Free - Posts Today: 2



Calmare Therapuetics Incorporated.,  (OTCQX: CTTC)

MAYO CLINIC News on Calmare (November, 2014)  



Scrambler Therapy for the management of chronic pain.

Author information

  • 1Internal Medicine, Mayo Clinic, Rochester, MN, USA.
    2Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA.
    3Medical University of South Carolina, Charleston, SC, USA.
    4Pain Medicine, MD Anderson Cancer Center, Houston, TX, USA.
    5Medical Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
    6Neurology, Mayo Clinic, Rochester, MN, USA.
    7Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA.
    8West Lynn Family Health Center, West Lynn, OR, USA.
    9Salve Regina University, Newport, RI, USA.
    10Medical Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.



Chronic pain is a widespread and debilitating condition, encountered by physicians in a variety of practice settings. Although many pharmacologic and behavioral strategies exist for the management of this condition, treatment is often unsatisfactory. Scrambler Therapy is a novel, non-invasive pain modifying technique that utilizes trans-cutaneous electrical stimulation of pain fibers with the intent of re-organizing maladaptive signaling pathways. This review was conducted to further evaluate what is known regarding the mechanisms and mechanics of Scrambler Therapy and to investigate the preliminary data pertaining to the efficacy of this treatment modality.


The PubMed/Medline, SCOPUS, EMBASE, and Google Scholar databases were searched for all articles published on Scrambler Therapy prior to November 2015. All case studies and clinical trials were evaluated and reported in a descriptive manner.


To date, 20 reports, of varying scientific quality, have been published regarding this device; all but one small study, published only as an abstract, provided results that appear positive.


The positive findings from preliminary studies with Scrambler Therapy support that this device provides benefit for patients with refractory pain syndromes. Larger, randomized studies are required to further evaluate the efficacy of this approach.


Chemotherapy-induced peripheral neuropathy; Chronic pain; Pain; Scrambler Therapy

[PubMed - in process]
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CTTC News: Quarterly Report (10-q) 05/19/2016 12:10:29 PM
CTTC News: Notification That Quarterly Report Will Be Submitted Late (nt 10-q) 05/17/2016 01:05:21 PM
CTTC News: Annual Report (10-k) 04/14/2016 05:34:55 PM
CTTC News: Notification That Annual Report Will Be Submitted Late (nt 10-k) 03/31/2016 04:34:14 PM
CTTC News: Quarterly Report (10-q) 03/01/2016 09:28:57 AM
#13523   You wanted studies. There they are. Pretty soon powderbum 05/25/16 09:43:02 AM
#13522   Support Care Cancer. 2016 Jun;24(6):2807-14. doi: 10.1007/s00520-016-3177-3. andy55q 05/25/16 06:36:15 AM
#13521   Because it needs Clinical Trials and FDA approval!! andy55q 05/24/16 07:57:33 AM
#13520   Something has to fill this void. Why not Calmare? powderbum 05/23/16 11:04:32 AM
#13519   Calmare Therapeutics Incorporated Uplists andy55q 05/23/16 10:03:05 AM
#13518   How oxy became the drug of choice, It powderbum 05/22/16 11:59:52 AM
#13517   Studio rileva molti pazienti che abusano di droghe andy55q 05/20/16 05:16:18 PM
#13516   Study finds many patients abusing drugs and alcohol conix 05/20/16 11:26:18 AM
#13514   Calmare Therapeutics annuncia primo trimestre 2016 risultati andy55q 05/20/16 06:55:20 AM
#13513   Il trattamento con il dispositivo Scrambler Therapy evita andy55q 05/19/16 07:59:42 AM
#13512   JUDGMENT WITHOUT TRIAL-PRACTICE BOOK SECTION 17-23 ET SEQ andy55q 05/19/16 07:53:26 AM
#13511   È calmare o Scrambler Therapy ??? andy55q 05/19/16 06:51:21 AM
#13510   Is it Calmare or Scrambler Therapy??? andy55q 05/18/16 07:59:20 AM
#13508   Notifica che relazione trimestrale sarà presentata tardivamente ( andy55q 05/17/16 07:57:53 PM
#13507   La porta è spalancata per calmare ? andy55q 05/17/16 07:56:21 PM
#13506   The Door is wide open for Calmare powderbum 05/17/16 04:34:06 PM
#13505   After having dug to a depth of 10 andy55q 05/16/16 08:30:52 PM
#13504   Non possiamo tutti solo andare d'accordo ? andy55q 05/16/16 08:07:22 PM
#13503   Can't we all just get along? conix 05/16/16 10:50:28 AM
#13502   It's managements responsibility to get the word out!! andy55q 05/16/16 06:46:43 AM
#13501   America is screaming for a solution. And we powderbum 05/15/16 04:09:07 PM
#13500   The future of pain relief will be ‘technaceuticals,’ powderbum 05/15/16 08:06:07 AM
#13499   The Worm has turned. The Cat is never powderbum 05/13/16 10:20:42 AM
#13498   Device Classification Name Stimulator, Nerve, Transcutaneous, For Pain Relief andy55q 05/11/16 02:04:02 AM
#13497   510(k) Premarket Notification - U.S. Food and Drug Administration andy55q 05/11/16 01:41:23 AM
#13496   Scrambler therapy andy55q 05/11/16 01:36:13 AM
#13495   The Company’s Distribution Rights for the Calmare Device andy55q 05/11/16 01:31:28 AM
#13494   DIS&L's sales force is now in 27 states. Deceived 05/11/16 12:30:30 AM
#13493   What a bunch of Crap powderbum 05/10/16 05:47:30 PM
#13492   Pain Care Clinic of Idaho (PCCID) near Boise, andy55q 05/10/16 02:51:53 PM
#13491   Scrambler Therapy® Technology MC-5A Device in the US. andy55q 05/10/16 02:42:29 PM
#13490   Study finds many patients abusing drugs and alcohol conix 05/09/16 03:29:46 PM
#13489   Calmare Therapeutics Receives Final Signatures on Supply Order conix 05/06/16 11:10:41 AM
#13488   Prince’s doctor to appear at American Pain Society conix 05/06/16 11:06:56 AM
#13487   Thanks, BigSpirit. conix 05/06/16 11:01:14 AM
#13486   Final signatures received on the supply order contract. nex9k 05/05/16 07:03:24 PM
#13485   Agree. I think you and Connix should be running Bigspirit1 05/04/16 06:32:45 PM
#13484   great information, thanks for posting. powderbum 05/04/16 02:23:24 PM
#13483   1.An exploratory study on the effectiveness of "Calmare andy55q 05/04/16 07:23:07 AM
#13482   An exploratory study on the effectiveness of "Calmare conix 05/03/16 11:06:53 AM
#13481   Can the compliance officer help CTTC comply with Bigspirit1 05/02/16 11:10:08 AM
#13480   Me too. The product is there. Bigspirit1 04/29/16 08:15:45 PM
#13479   I would just like to see it become conix 04/29/16 04:04:54 PM
#13478   How much of the 300 billion spent on powderbum 04/29/16 09:28:28 AM
#13477   Thank you. Bigspirit1 04/27/16 02:46:26 PM
#13476   Thank you. Bigspirit1 04/27/16 02:46:25 PM
#13475   I understand that the Feds are investigating Marineo conix 04/26/16 12:13:41 PM
#13474   why have there been no sales under the Bigspirit1 04/23/16 08:58:03 AM
#13473   Anyone here know how to file with the gnc1976 04/22/16 10:06:32 AM
#13472   LOL Oh yes SUCH GREAT AMAZING and FANTASTIC gnc1976 04/21/16 08:46:21 PM