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Calmare Therapeutics Inc. (CTTC)

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Last Post: 10/24/2016 6:51:22 PM - Followers: 36 - Board type: Free - Posts Today: 0



Calmare Therapuetics Incorporated.,  (OTCQX: CTTC)

MAYO CLINIC News on Calmare (November, 2014)  



Scrambler Therapy for the management of chronic pain.

Author information

  • 1Internal Medicine, Mayo Clinic, Rochester, MN, USA.
    2Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA.
    3Medical University of South Carolina, Charleston, SC, USA.
    4Pain Medicine, MD Anderson Cancer Center, Houston, TX, USA.
    5Medical Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
    6Neurology, Mayo Clinic, Rochester, MN, USA.
    7Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA.
    8West Lynn Family Health Center, West Lynn, OR, USA.
    9Salve Regina University, Newport, RI, USA.
    10Medical Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.



Chronic pain is a widespread and debilitating condition, encountered by physicians in a variety of practice settings. Although many pharmacologic and behavioral strategies exist for the management of this condition, treatment is often unsatisfactory. Scrambler Therapy is a novel, non-invasive pain modifying technique that utilizes trans-cutaneous electrical stimulation of pain fibers with the intent of re-organizing maladaptive signaling pathways. This review was conducted to further evaluate what is known regarding the mechanisms and mechanics of Scrambler Therapy and to investigate the preliminary data pertaining to the efficacy of this treatment modality.


The PubMed/Medline, SCOPUS, EMBASE, and Google Scholar databases were searched for all articles published on Scrambler Therapy prior to November 2015. All case studies and clinical trials were evaluated and reported in a descriptive manner.


To date, 20 reports, of varying scientific quality, have been published regarding this device; all but one small study, published only as an abstract, provided results that appear positive.


The positive findings from preliminary studies with Scrambler Therapy support that this device provides benefit for patients with refractory pain syndromes. Larger, randomized studies are required to further evaluate the efficacy of this approach.


Chemotherapy-induced peripheral neuropathy; Chronic pain; Pain; Scrambler Therapy

[PubMed - in process]
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CTTC News: Proxy Statement (definitive) (def 14a) 10/25/2016 05:32:03 PM
CTTC News: Quarterly Report (10-q) 08/22/2016 04:46:51 PM
CTTC News: Notification That Quarterly Report Will Be Submitted Late (nt 10-q) 08/15/2016 04:00:46 PM
CTTC News: Quarterly Report (10-q) 05/19/2016 12:10:29 PM
CTTC News: Notification That Quarterly Report Will Be Submitted Late (nt 10-q) 05/17/2016 01:05:21 PM
News News Alert: Proxy Statement (definitive) (def 14a) 10/25/2016 05:32:03 PM
#13693   Depends if you get a Pocket Fisherman too. conix 10/24/16 06:51:22 PM
#13692   How many shares of Calmare do you get mog1962 10/24/16 04:30:40 PM
#13691   Looks like Conrad has been busy. conix 10/24/16 11:07:17 AM
#13690   Great News report on patient from Australia successfully powderbum 10/21/16 03:12:24 PM
#13689   you need a bit more understanding of rigorous mog1962 10/21/16 12:20:32 PM
#13688   It'a not as complicated as you are making powderbum 10/21/16 10:37:23 AM
#13687   powderbum Not to be unkind, but: mog1962 10/20/16 02:48:47 PM
#13686   Don't forget about two important studies out there: powderbum 10/20/16 02:38:07 AM
#13685   I agree with all your points MOG. Bigspirit1 10/19/16 07:06:11 PM
#13684   Johnnie Johnson is lucky he is not wearing conix 10/19/16 12:34:52 PM
#13683   Accumulating shares at this level is not a mog1962 10/19/16 10:56:09 AM
#13682   Things just seem to get "better". I am conix 10/18/16 03:24:04 PM
#13681   I don't want to say what I think Bigspirit1 10/18/16 11:48:49 AM
#13680   Why do you refer to this as a mog1962 10/13/16 04:21:43 PM
#13679   Calmare Real Time, giving people their lives back powderbum 10/13/16 10:12:37 AM
#13678   Some Med Schools are changing the way they powderbum 10/13/16 09:46:44 AM
#13677   Sidelined No More - Scrambler Therapy Puts Tess conix 10/12/16 10:42:55 PM
#13676   Mayo Clinic Story powderbum 10/12/16 02:59:47 AM
#13675   Calmare Finally getting a deserved high-lite: powderbum 10/12/16 02:46:12 AM
#13674   This is what it's like seeing a Calmare powderbum 10/12/16 02:32:24 AM
#13673   Insurance Coverage powderbum 10/12/16 02:14:23 AM
#13672   The Mayo misunderstanding was not made public. Bigspirit1 10/11/16 04:24:12 PM
#13671   Johnnie Johnson is my man. Bring him back. conix 10/11/16 01:37:05 PM
#13670   I'm getting in when they bring John Nano back!! andy55q 10/11/16 11:51:51 AM
#13669   I am aiming to get back in at conix 10/11/16 11:04:25 AM
#13668   When did that information appear? I have mog1962 10/10/16 04:32:17 PM
#13667   Andy55, Bigspirit1 10/08/16 10:32:50 AM
#13666   What?? Refuse to pay Mayo Clinic !! andy55q 10/07/16 01:58:07 PM
#13665   So here is the update from the story powderbum 10/07/16 12:02:16 PM
#13664   I am glad that the patients will benefit. Bigspirit1 10/07/16 09:45:22 AM
#13663   That is pretty impressive. To have Calmare mentioned conix 10/06/16 09:22:26 AM
#13662   Let's get some NEWS! How about an update Cats83 10/05/16 04:04:24 PM
#13661   Calmare gets it's 1st mention on website: powderbum 10/05/16 03:57:29 PM
#13660 powderbum 10/05/16 09:59:50 AM
#13659 powderbum 10/05/16 09:59:50 AM
#13658   Good questions. Posted the answers when you receive them!! andy55q 10/04/16 08:58:01 AM
#13657   There are no shortcuts with insurance reimbursement nor conix 10/03/16 06:39:52 PM
#13656   Amen !! andy55q 10/01/16 10:15:55 PM
#13655   I agree with Bigspirit1. mog1962 10/01/16 02:53:40 PM
#13654   I have seen the enemy, and they is Bigspirit1 09/29/16 03:24:55 PM
#13653   What a screwed up industry! The door is powderbum 09/28/16 11:49:48 AM
#13652   I agree. I believe all of us Bigspirit1 09/27/16 05:00:08 PM
#13651   What an incredible story! There isn't a technology powderbum 09/27/16 10:02:46 AM
#13650   Emily Hewatt leaves to seek treatment for CRPS andy55q 09/26/16 08:36:19 AM
#13649   Sorry, but I cannot follow your logic on mog1962 09/23/16 01:39:50 PM
#13648   My point was that if they get approval powderbum 09/22/16 09:34:38 PM
#13647   Mog,I agree andy55q 09/22/16 02:40:53 PM
#13646   I believe that ownership claim is open to mog1962 09/22/16 12:43:50 PM
#13645   Something to keep an eye on: We own powderbum 09/22/16 09:05:39 AM
#13644   How much money can you lose if you Bigspirit1 09/22/16 08:53:34 AM