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Calmare Therapeutics Inc. (CTTC)

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Last Post: 6/22/2017 5:39:41 PM - Followers: 36 - Board type: Free - Posts Today: 2



Calmare Therapuetics Incorporated.,  (OTCQX: CTTC)

MAYO CLINIC News on Calmare (November, 2014)  



Scrambler Therapy for the management of chronic pain.

Majithia N1, Smith TJ2, Coyne PJ3, Abdi S4, Pachman DR5, Lachance D6, Shelerud R7, Cheville A7, Basford JR7, Farley D8, O'Neill C5, Ruddy KJ5, Sparadeo F9, Beutler A5, Loprinzi CL10.

Author information

  • 1Internal Medicine, Mayo Clinic, Rochester, MN, USA.
    2Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA.
    3Medical University of South Carolina, Charleston, SC, USA.
    4Pain Medicine, MD Anderson Cancer Center, Houston, TX, USA.
    5Medical Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
    6Neurology, Mayo Clinic, Rochester, MN, USA.
    7Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA.
    8West Lynn Family Health Center, West Lynn, OR, USA.
    9Salve Regina University, Newport, RI, USA.
    10Medical Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.



Chronic pain is a widespread and debilitating condition, encountered by physicians in a variety of practice settings. Although many pharmacologic and behavioral strategies exist for the management of this condition, treatment is often unsatisfactory. Scrambler Therapy is a novel, non-invasive pain modifying technique that utilizes trans-cutaneous electrical stimulation of pain fibers with the intent of re-organizing maladaptive signaling pathways. This review was conducted to further evaluate what is known regarding the mechanisms and mechanics of Scrambler Therapy and to investigate the preliminary data pertaining to the efficacy of this treatment modality.


The PubMed/Medline, SCOPUS, EMBASE, and Google Scholar databases were searched for all articles published on Scrambler Therapy prior to November 2015. All case studies and clinical trials were evaluated and reported in a descriptive manner.


To date, 20 reports, of varying scientific quality, have been published regarding this device; all but one small study, published only as an abstract, provided results that appear positive.


The positive findings from preliminary studies with Scrambler Therapy support that this device provides benefit for patients with refractory pain syndromes. Larger, randomized studies are required to further evaluate the efficacy of this approach.


Chemotherapy-induced peripheral neuropathy; Chronic pain; Pain; Scrambler Therapy

[PubMed - in process]
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CTTC News: Notification That Annual Report Will Be Submitted Late (nt 10-k) 03/31/2017 04:42:45 PM
CTTC News: Current Report Filing (8-k) 03/23/2017 04:57:51 PM
CTTC News: Current Report Filing (8-k) 02/23/2017 04:18:20 PM
CTTC News: Statement of Ownership (sc 13g) 02/14/2017 06:09:53 AM
CTTC News: Quarterly Report (10-q) 12/29/2016 04:09:07 PM
#14189   Is there a punch line if we answer mog1962 06/22/17 05:39:41 PM
#14188   Anyone hear about a private investigator retained by conix 06/22/17 12:55:33 PM
#14187   Powderbum has gone quiet as these legal issues mog1962 06/21/17 12:24:44 PM
#14186   Speaking of lawsuits, CTTC has only until June nobodysbusiness 06/21/17 09:28:23 AM
#14185   The calmare lineup: nobodysbusiness 06/20/17 10:28:39 PM
#14184   No doubt it'll make a great excuse for nobodysbusiness 06/20/17 05:11:28 PM
#14183   Are both of the lawsuits identified in recent mog1962 06/20/17 04:21:38 PM
#14182   Actually, I think the lawsuit might be helpful....Helpful conix 06/20/17 11:13:30 AM
#14181   "William Austin Lewis"? I take it that is nobodysbusiness 06/20/17 10:47:21 AM
#14180   Oh, lordy! Not ANOTHER lawsuit! Lawyers seem nobodysbusiness 06/20/17 10:43:04 AM
#14179   Not good. ??? andy55q 06/20/17 09:21:07 AM
#14178   'Phantom Pain' Device Maker Misled Investors, Suit Says conix 06/20/17 09:11:28 AM
#14177   Calmare Therapeutics faces investor suit alleging mismanagement conix 06/20/17 09:03:50 AM
#14176   Give him a box to stand on!! andy55q 06/19/17 01:28:00 PM
#14175   Lots of progress conix 06/19/17 12:28:19 PM
#14174   Conrad Mir, CEO of Calmare Therapeutics. Please resign. conix 06/19/17 09:57:47 AM
#14173 where's the 10-K? nobodysbusiness 06/16/17 04:57:10 PM
#14172 powderbum 06/16/17 11:24:31 AM
#14171   1st MD Anderson, Now Calmare is spreading to powderbum 06/16/17 10:26:05 AM
#14170   Does it concern you at all that CTTC conix 06/16/17 09:43:48 AM
#14169   Value based medicine Doesn't just apply to drugs. powderbum 06/16/17 12:51:48 AM
#14168   The BEST policy right now would be to nobodysbusiness 06/15/17 10:14:36 PM
#14167   powderbum did I miss the portion of the text mog1962 06/15/17 06:46:57 PM
#14166   Dream on !! andy55q 06/15/17 06:32:17 PM
#14165   One policy being discussed for inclusion in the powderbum 06/15/17 04:44:43 PM
#14164   Based upon that info, I would also be mog1962 06/15/17 04:35:13 PM
#14163   Competitive Technologies Names New CEO conix 06/15/17 02:18:59 PM
#14162   Powderbum I doubt that anyone on this board questions mog1962 06/15/17 10:50:19 AM
#14161 powderbum 06/15/17 09:06:13 AM
#14160   He is a bit of a bottom feeder mog1962 06/15/17 12:47:05 AM
#14159   Who in their right mind would buy a nobodysbusiness 06/14/17 06:40:42 PM
#14158   lack of financials hurts mog1962 06/14/17 02:20:39 PM
#14157 powderbum 06/13/17 07:33:53 PM
#14156   By the way, I must have missed the mog1962 06/13/17 10:50:08 AM
#14155   Bad management, perhaps? conix 06/12/17 10:51:35 PM
#14154   OK PB, There could be green tape painters Munchqin 06/12/17 10:28:47 PM
#14153   Paying the electric bill? nobodysbusiness 06/12/17 09:04:51 PM
#14152   Why is someone down ticking the stock on powderbum 06/12/17 12:52:14 PM
#14151   I agree but why are we at .12? andy55q 06/11/17 10:35:20 PM
#14150   I do not expect anyone who has not conix 06/11/17 09:53:37 PM
#14149   Please don't be silly. The worldwide chronic pain nobodysbusiness 06/11/17 11:30:29 AM
#14148   You are wrong and have no idea what powderbum 06/11/17 09:32:40 AM
#14147   You can only get stories like this with Calmare: powderbum 06/11/17 08:49:33 AM
#14146   No, Occam's Razor explanation as to why "no nobodysbusiness 06/10/17 08:32:44 PM
#14145   Mog, you are correct. Studies are needed to andy55q 06/10/17 06:22:04 PM
#14144   powderbum No one should disagree with the need to mog1962 06/10/17 04:44:35 PM
#14143   Tide is turning for The FDA ans AMA. powderbum 06/10/17 01:26:36 PM
#14142   No need to cancel them since he has mog1962 06/09/17 12:32:04 PM
#14141   What did he do now ?? andy55q 06/09/17 07:56:06 AM
#14140   The company should cancel the shares that Mir has. conix 06/08/17 09:52:39 PM