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AngioGenex, Inc. (AGGX)

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Last Post: 8/3/2016 7:50:41 AM - Followers: 9 - Board type: Free - Posts Today: 0

Developing a novel, patented anti-cancer agent that also may be effective treating age related macular generation, rheumatoid arthritis and some symptoms of diabetes. 
Their lead researcher's lab is at Memorial Sloan Kettering. Robert Benezra PhD.
MSK and Benezra are also investors/shareholders.

AGGX has patented technology here 
"Uncovering new functions of a gene implicated in cancer growth opens new therapeutic possibilities 
Date: April 29, 2015 
Source: Weill Cornell Medical College 
Summary: For the first time, researchers have shown that a gene previously implicated in blood vessel formation during embryonic development and tumor growth also induces immune suppression during tumor development. This finding opens the door for new therapeutic approaches and vaccine development in treating patients with melanoma and other advanced-staged cancers." 


http://www.sciencedaily.com/releases/2015/04/150429145458.htm 

AngioGenex is a biopharmaceutical company formed to pursue the discovery and development of proprietary products for the treatment, diagnosis and prognosis of cancer. While there are numerous companies that have the same objective, none have the unique, patented technology that is being exploited by AngioGenex. 
The target of the AngioGenex drug discovery effort is a previously unrecognized biological process necessary to support tumor growth that emerged from one of the most famous cancer laboratories, Memorial Sloan Kettering Cancer Center, NYC. Dr. Robert Benezra, a distinguished member of this institute, discovered that certain genes (Id genes) are actively involved in fetal growth and can be inappropriately activated in the adult to support the growth and spread of tumors. He showed that tumor growth is markedly inhibited if these genes or their proteins are even partially inactivated. 
In collaboration with Dr. Benezra, AngioGenex has successfully pursued the discovery and development of molecules that inhibit the Id proteins and block tumor growth in animals. This research confirms that the Id genes are the controlling, master genes, in a unique and previously unknown process that is required for the growth and spread of tumors. A profound inhibition of tumor growth is demonstrated in animals that either have the Id genes deleted by genetic manipulation or are treated with an anti-Id drug (See Figure below). 
An important finding is that the Id genes are structurally almost identical in humans as in animals suggesting that the anti-tumor effects of Id drug observed in animals will also occur in humans. 

http://www.angiogenex.com/technology.html 

http://www.angiogenex.com/patents.html
 
http://www.angiogenex.com

A/S is 150,000,000 Last known outstanding 21,302,906 as of 11/27/2009 (likely more now)

The Robert Benezra lab at Memorial Sloan Kettering

https://www.mskcc.org/research-areas/labs/robert-benezra

Recent deal with The Trout Group for awareness and funding
http://www.troutgroup.com/clients/overview

 
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#34  Sticky Note Developing a novel, patented anti-cancer agent that also e-ore 02/03/16 09:59:32 AM
#67   Yes, lots of risk here. e-ore 08/03/16 07:50:41 AM
#66   Yeah but it's a form 15 filer. What protagonist12 08/03/16 07:33:36 AM
#65   As usual with me it's about the "what e-ore 08/02/16 07:42:16 AM
#63   I don't know e-ore still just a Form protagonist12 08/02/16 03:57:05 AM
#62   They haven't filed anything but have put out e-ore 07/31/16 04:59:34 PM
#61   Interesting stawk here... would be nice to see Golf4Food 07/31/16 02:52:26 PM
#60   About $50,000 worth of trading in the last e-ore 07/25/16 03:09:10 PM
#59   .55 a buying point if you still believe e-ore 07/21/16 02:07:25 PM
#58   New to the board, say hello to everyone. lifeisagamble 07/18/16 02:41:49 PM
#57   Thanks. Have a good weekend and glty e-ore 07/15/16 03:55:32 PM
#56   beautiful.. don't see enough of these big movers anymore db7 07/15/16 03:32:43 PM
#55   Make it 8, hit .85 e-ore 07/15/16 02:52:44 PM
#54   .80 now. 7th new 52 week high since 6/20 e-ore 07/15/16 01:44:00 PM
#53   Mini volume but another 52 week high. .75 e-ore 07/14/16 01:21:45 PM
#52   Thanks. Glty e-ore 07/12/16 03:32:09 PM
#51   nice job on this one e-ore! db7 07/12/16 03:25:59 PM
#50   10,000 more shares today, now .50 e-ore 07/12/16 03:04:27 PM
#49   5000 shares today so far. Another 52 week e-ore 07/12/16 01:11:45 PM
#48   Only 100 shares but the 4th new 52 e-ore 07/11/16 03:12:55 PM
#47   AGGX filed annual list at Nevada 7/08, was e-ore 07/11/16 08:19:57 AM
#46   Mini volume but another 52 week high fwiw. e-ore 07/06/16 12:11:23 PM
#45   Another new 52 week high .31 fwiw e-ore 06/28/16 03:13:00 PM
#44   AGGX deregistered via a 15-12 in 2010, going e-ore 06/23/16 09:06:42 AM
#43   New 52 week high .30 fwiw e-ore 06/20/16 10:45:25 AM
#42   .20 x .30 now e-ore 06/07/16 12:12:48 PM
#41   AGGX - Major changes here over the last e-ore 06/06/16 11:45:33 PM
#40   Website not updated yet but ownership and contact e-ore 05/03/16 09:56:03 AM
#39   AGGX - .25 now with some volume in e-ore 04/07/16 10:50:38 AM
#38   L2 activity has been very quiet here lately. e-ore 03/14/16 12:27:44 PM
#37   After yesterday's nibbling NITE now at .30 on e-ore 02/23/16 10:55:54 AM
#36   Some nibbling today. Maybe we'll see the website e-ore 02/22/16 02:12:52 PM
#35   Noticed that the AGGX logo has changed in e-ore 02/09/16 12:22:25 PM
#34   Developing a novel, patented anti-cancer agent that also e-ore 02/03/16 09:59:32 AM
#33   AGX-51 patented by AGGX. Dr Benezra is AGGX's e-ore 01/27/16 10:46:35 PM
#32   Been adding a little here at .09 e-ore 01/25/16 10:39:42 AM
#31   AGGX website under construction. e-ore 01/23/16 05:16:32 PM
#29   Uncovering new functions of a gene implicated in e-ore 01/11/16 11:55:54 PM
#28   "Our intention to initiate clinical trials with our e-ore 01/11/16 11:45:50 PM
#27   OS likely to be higher since they have e-ore 01/09/16 08:52:56 AM
#26   Do you think 21m OS is still valid? Axel 01/09/16 01:45:35 AM
#25   Website being updated again. Was updated about a e-ore 01/09/16 01:27:01 AM
#24   Interesting that Robert Benezra PhD is an AGGX e-ore 09/08/15 11:13:31 PM
#23   AGGX has patented technology here e-ore 07/27/15 10:58:07 AM
#22   My personal opinion is that AGGX will resume e-ore 06/08/15 09:10:21 PM
#21   Chief research scientist for AGGX is Robert Benezra, e-ore 06/08/15 09:05:09 PM
#20   I know this company is "dark" but there's e-ore 06/08/15 08:56:22 PM
#19   AGGX - Biggest volume in almost a year. e-ore 06/08/15 08:45:28 PM
#18   AGGX 2015 product pipeline report just released. Not e-ore 04/27/15 08:19:58 AM
#17   First time I've seen diabetes and rheumatoid arthritis e-ore 04/06/15 10:32:18 AM
#16   Website updated. Mostly the same info, different look e-ore 03/31/15 01:00:01 PM
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