stoneroad, thanks. Big pharma and everyone else knows cancer is a genetic event, and it will be gene therapy which turns it around. Meanwhile, with the reality of dying people requiring some sort of treatment, it is a question of what works best now...and immunotherapy ain't it. We went down theimmunology path almost 50 years ago with BCG and melanoma. Granted, results are (incrementally) better, and we have a hugely greater understanding of the immune system, but solid cancers big enough to be seen and felt, if surgically accessible, need to be removed. Bavi has a GREAT future if it can be used diagnostically to light up early tumors, and therapeutically to help slow growth of metastases and prevent recurrence. That last 1/2 sentence is enormous. Therefore I am more optimistic than ever about Bavi. The Brekken papers were huge. I don't need to repeat that if I were throwing resources at one or the other-- a trial of Yervoy + Bavi, or irradiation + Bavi--it would be the latter in a heartbeat.
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