My reaction would be, given the apparent stellar success of Phase 1, coupled with the protective patents and the staggering revenue potential represented, a major event like noted, would be enough to get the share price to a point that the approved RS would be doable; that could happen at anytime and is exactly why at this critical time, to be out of the stock, or not fully positioned, would be a major mistake.
Nobody rings a bell beforehand. When the bell rings, given the above, it's too late to get ACTC at these prices, but not too late to still own it, imo.