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biomaven0

02/13/14 10:38 PM

#174208 RE: Bulbaman #174207

>>Shkreli seemed pretty confident Chenodal would work as well as Intercept’s drug for PBC & NASH

Hard for me to imagine that is true, even though I wish it was given I own RTRX in both real life and in the SI charity portfolio with a big weighting. 100x better potency (implying a much lower dose) very likely buys you some safety and tolerability advantages too.

See P9 of this presentation:

http://www.interceptpharma.com/pdf/Adorini.EASL.April2013.pdf

Aside from anything else, the pricing difference would make other indications very difficult.

Peter