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Replies to post #172972 on Biotech Values
iwfal
01/21/14 10:03 AM
#172981 RE: nuere #172972
There are 3 IL-1 inhibitors on the market associated with the ligand/receptor signaling interaction, anakinra (Kineret; Amgen/Biovitrum), canakinumab (Ilaris; Novartis) and rilonacept (Arcalyst; Regeneron). Anakinra and rilonacept inhibits the effect of IL-1alpha as well as those of beta. As I understand it, diacerein/rhein prevents, the formation of IL-1beta and not the receptors.