Replies to post #171819 on Biotech Values

[jq1234]

How's CF101 profile compared to Apremilast?

[mcbio]

CANF

Anyway, I don't see the drug competing with anti-TNFs or even JAK inhibitors, but as monotherapy alternative to methotrexate, in patients who have failed or are refractory to methotrexate or cannot tolerate it (CF101 has a much better safety profile).

What's to prevent patients who have failed or are refractory to methotrexate from simply using anti-TNFs or JAK inhibitors, particularly if the latter have better efficacy and/or are at least as safe as CF101?