Crow3, wrong. Relevant, because the whole point was the earlier generations of ValiMed worked in the UV portion of the EM spectrum, and used only fluorescence. That was part of my point...not used for NaCl. However, now the ValiMed G4 is more toward the InfraRed (IR/NIR). My point was the EARLIER generations of ValiMed were would have been inappropriate for NaCL analysis in my opinion.
Because the ValiMed G4 system employs Raman and Spectral Reflection, (as well as fluorescence), take a look at Raman in the IR/NIR as it applies to NaCL, combine what you learn with the fluorescence (or lack thereof, which would actually be part of the 3-facet signature used by the VG4), and then (importantly) look at NaCl and spectral reflection. Look at what others have done, forget the fluorescence capability of the VG4 and focus on the Raman and reflectance aspects, and combine their capabilities.
You should find works with NaCl solutions via Raman spectroscopy and new optical sensors.
You should find works in the infrared referencing reflection spectrum of sodium chloride.
You should find NIR or IR spectroscopy work towards predicting sodium chloride content.
The fact is, when one refers to ValiMed, it is extremely important to specify which generation....There are multiple ValiMed generations.
Based upon what I know, I hold the opinion that the UV fluorescence generations would not apply, but a laser-based system working in the IR or NIR that employees a combination of Raman Spectroscopy+Spectral Reflectance, well it just might have strong potential for working with NaCl.
Forget the potential, and lets consider the facts.
Here is what we know as FACT:
1) CDEX expects to be able to begin working toward analysis of TPN products (parenteral nutrition) using the ValiMed G4. This is well documented based upon their SEC filings and the patent application information.
2. NaCl, sodium chloride, is a big deal with TPNs. Consider:
Another tragic parenteral nutrition compounding error
Problem: In our newsletter two weeks ago, we highlighted a tragic story about contaminated parenteral nutrition (PN) from a compounding pharmacy that led to nine deaths.1 Around the same time, another tragic outcome with PN was making the headlines, this one involving a 6-week old infant who died late in 2010 after receiving a PN solution that contained 60 times more sodium than prescribed
= = = = = =
Connect those two.
If CDEX has confidence that TPNs can be processed, and that includes NaCl, then it is reasonable to suspect there is potential for the ValiMed G4 system to evaluate NaCl. I don't know if Raman spectroscopy or Spectral Reflectance would be the more important approach, or if the combination of the two is a key, but it seems there is potential. We will all know one way or the other some day, but until we see a list of drugs, solutions, compounds, etc that the ValiMed G4 system can process, it will remain educated speculation.
At lease we agree on the UV based Fluoresence-only generations would not be applicable to NaCl. ValiMed G4 potential with NaCl will only be seen when CDEX wants it to be seen, assuming that potential exists. The fact is, these two organizations have some form of partnership and the foundation must see potential too.
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