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Replies to post #103641 on Cannabis Science Inc (fka CBIS)
09/30/13 4:50 PM
Yervoy in Detail - Patient Information: Side Effects
Yervoy (ipilimumab) is a monoclonal antibody used to treat late-stage, metastatic melanoma, a deadly skin cancer. Yervoy is thought to work by allowing the body's immune system to recognize, target, and attack cells in these tumors. Patients with metastatic melanoma are shown to live longer when treated with Yervoy. Side effects of Yervoy can include enterocolitis, decreased liver function, and dermatitis.
Yervoy is administered intravenously over 90 minutes every 3 weeks for a total of four doses. It is not known whether Yervoy is secreted in human milk. Breastfeeding mothers should carefully consider the potential for serious adverse reactions in nursing infants. A decision should be made to discontinue nursing or to discontinue Yervoy. Safety and effectiveness of YERVOY have not been established in pediatric patients.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Serious and sometimes fatal reactions may occur during treatment with ipilimumab or months after stopping. Contact your doctor right away if you have symptoms such as:
diarrhea, increased bowel movements, black or bloody stools, stomach tenderness; pain in your upper stomach, dark urine, jaundice (yellowing of the skin or eyes), easy bruising or bleeding; unusual muscle weakness, numbness or tingling in your hands or feet; unusual headaches, feeling cold or tired, weight gain, dizzy spells, mood changes, irritability, confusion; mouth sores, skin rash with or without itching, blistering or peeling, skin sores with bleeding; or eye pain, or vision problems.
Call your doctor at once if you have any of these other serious side effects:
severe stomach pain, bloating, constipation, or vomiting;
having several more bowel movements per day than before you started receiving ipilimumab;
loss of bowel control;
trouble with daily activities;
feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
urinating less than usual or not at all;
severe upper stomach pain spreading to your back, nausea and vomiting, fast heart rate;
fever, cough, trouble breathing; or
chest pain, feeling short of breath (even with mild exertion), swelling, rapid weight gain.
Less serious side effects may include:
feeling tired;
mild diarrhea; or
mild skin rash or itching.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
10/01/13 1:02 PM
