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Truthbythought

09/16/13 4:18 PM

#41806 RE: cabel #41804

The other drug had an issue I think with hypotension (unsafe drop in blood pressure). This one had a few people discontinued because blood pressure got above 180 per the poster. The one who had hypertension (high blood pressure) in the low dose group had a history of hypertension.

mdphd2008

09/16/13 4:37 PM

#41815 RE: cabel #41804

In patients experiencing severe systemic bacterial infections - sepsis - it often leads to septic shock - where patients may experience - severe HYPOtension requiring powerful medications to artificially raise the blood pressure (pressors). I wonder if "B" was so efficacious that it resolved their septic shock by eradicating bacterial infection before the physicians had a chance to stop
the infusion of pressors!! Regardless, as a clinician that has dealt with patients experiencing sepsis - I am always much more concerned with hypotension (decrease perfusion and oxygenation to vital organs - brain, kidneys, extremities) than hypertension, which may actually be a beneficial side effect!!!! I was LONG before the acquisition and now I am LONG and EXCITED!!! Keep the good news coming!!!!