Replies to post #135883 on Avid Bioservices Inc (CDMO)

[biopharm]

United States navy with the help of a pharmaceutal company has come up with a vaccine for maleria which will be tested on thousands of people. Bavi doesn't work on parasites does it ? :) or can avid provide the drug for the upcoming trials ?

If that ends up happening... I'd say Walter Reed MMC will be part of the mix: close to Washington... Bethesda, MD ... lots of connections between the two and some Doctors there probably knowing very well that Bavi works.... and works well.

Walter Reed National Military Medical Center is the Nation’s Medical Center, proudly serving military beneficiaries in the Washington, D.C. area as well as those from across the country and around the globe. As the largest military medical center in the U.S., we are a tertiary care destination providing services in over 100 clinics and specialties. We are proud to be known as the first destination in the continental United States for caring for the wounded, ill and injured from global conflicts.

Walter Reed National Military Medical Center (WRNMMC) was established on November 10, 2011, as a result of the Base Realignment and Closure Act, which consolidated National Naval Medical Center and Walter Reed Army Medical Center on the grounds of the former NNMC campus in Bethesda, Maryland. The Medical Center combines the proud history and commitment to excellence of these two great Navy and Army medicine icons.

WRNMMC combines 170 years of providing outstanding compassionate care to war heroes and presidents alike.

http://www.wrnmmc.capmed.mil/SitePages/home.aspx
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What better compassionate care... than with Bavi. Time will tell.

[semper]

Ku Peregrines comments on malaria:

"Researchers have found that PS is exposed on the outer membrane of cells infected with HIV, influenza, herpes viruses, hemorrhagic fever viruses, respiratory syncytial virus, measles, and the smallpox and rabies virus families, as well as on cells infected with certain protozoan pathogens responsible for diseases including malaria and leishmaniasis. In preclinical studies, our lead PS-targeting antibody bavituximab has demonstrated the ability to bind to virus particles and virus-infected cells of five viruses that cause viral hemorrhagic fever (VHF), including the highly lethal Ebola virus. In data presented at the November 2010 Chemical and Biological Defense Science & Technology Conference, preclinical efficacy studies also showed that bavituximab in combination with the antiviral drug ribavirin improved survival in animals compared to either drug used alone in several models of VHF (view poster)."
http://www.peregrineinc.com/technology/bavituximab-antiviral/ps-targeting-data.html

[semper]

And here's more KU

Recent years have seen a surge in scientific publications investigating the occurrence of exposed phosphatidylserine (PS) during the infections caused by viruses and protozoan parasites. These groups of pathogens are responsible for many of the deadliest and most widespread diseases affecting mankind including AIDS and malaria.
Peregrine's PS targeting antibodies may address a common immune evasion mechanism exploited by infectious pathogens. Exposed PS is a subject of increasing study by researchers worldwide as a result of its thoroughly documented immunosuppressive activity, its active role in numerous infections, and its potential as a valid broad-spectrum therapeutic target.
http://www.peregrineinc.com/technology/bavituximab-antiviral.html