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Puffer

07/19/13 2:30 PM

#69950 RE: JG36 #69949

yes and that always involves alteration of cell function which is not the case here.
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drkazmd65

07/19/13 2:34 PM

#69951 RE: JG36 #69949

Yep,... that's the whole point of the TOX testing. If a prospective new drug or treatment causes significant harm early on, detectable in a small sample size,.... then what's the point of going onto additional study?

However - the fact that other PEG-based medicines and general chemicals have been tested previously and not generally found to cause cell damage or display general toxic characteristics in other applications does suggest that Toxicity isn't likely to be a short-term & chronic problem for Flucides, or the other 'cides.

It is unlikely that there will be a toxicity problem in humans if none has been noted to daet among mice for these formulations.

Still gotta CYA and get the data here.
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BonelessCat

07/19/13 3:34 PM

#69957 RE: JG36 #69949

Again you post proof that you don't know very much about the animal trials. All trials included multiple doses, not just one dose. Also, hybridized mice selected for these trials were chosen specifically because they are good models for human interaction with the drug. Dr. Menon is an expert in mouse wrangling for pre-clinical development and selection of species/hybrids that model humans.

There are lots of drugs that don't kill mice when you give them a single dose that turn out to be too toxic for human use.

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Echo20

07/19/13 11:44 PM

#69972 RE: JG36 #69949

JG36

How do you consider tht FLUCIDE did anything deadly to any mice?

There were thousands of tests at several locations.

In the testing the mice were knocked off later to disect.

In the last interview by Dr Seymour he stated he has made FLUCIDE to be used in primates on testing of H7N9 or MERS. Those tests should be very interesting.

Dr Seymour also stated NNVC performed over 5000 animal tests successfully without failure. Without toxic results. That is pretty good.

Echo20