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jaybe

06/18/13 12:33 AM

#162665 RE: biomaven0 #162664

"Conservative" was poor choice of words...

Meant something more like precise, by disclosing rational basis for target and mutations, with strong predictive pre-clinical data. Shouldn't single out Novartis either, as far as big pharmas go they have one of the better R&D outfits. Better example would be that Clovis poster for CO-1686, lacking in thoroughness, and too selective, emphasizing safety data for lower doses together with efficacy on higher doses.