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jaybe

06/16/13 11:13 AM

#162585 RE: biomaven0 #162583

I think the battle for best 2nd gen ALK inhibitors will be decided on durability of response, PFS and OS. I know '113 and LDK also have activity in brain mets, but moving the needle on PFS past 9.7 mos (Criz) will be the true test for a next generation ALK inhibitor. This means waiting another 12-18 months for '113 and Chugai/Roche to have such data to compare against LDK.