Bio and RRDog, I am glad I passed that ball into the field :)
But for what it is worth, it shows how difficult a discussion/negotiation between PPHM and a potential partner will be!
PPHM will kind of see the sky and approach the problem as if they get all the market and as if whiteout them nothing happens.
The partner will say, yes could well be but you cannot guarantee that!
And franckly, since RRDog brought up the risk factor, if I were a potential partner I would ask PPHM that they can guarantee that, even if we follow Bio's becoming SOC scenario, they can guarantee that the Bavi including SOC will not be beaten soon after!
I guess a partner will not write down pre-payments, milestones etc in one year of sales. they'll pay licenses and will spread the upfront costs. So yes high risk out of that corner too and it would be normal that it reflects in the partnership prices (downwards unless PPHM gives the guarantees or pre-payment shifted to longer term milestone such as "as long as this is the SOC").
I would like to be a fly on the wall to have a glimpse of how they negotiate this and who says what at that table. That would be a learning experience!