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volgoat

06/02/13 12:08 PM

#125428 RE: 2ndstr2thert #125427

Bavi does not bind directly to PS, but next generation will.
Imagine the difference.....Then keep imagining....and so on and so on.


Bavi targets PS by binding to 2 molecules of B2-glycoprotein-I that in turn bind to PS on the surface of cells.

entdoc

06/02/13 1:25 PM

#125437 RE: 2ndstr2thert #125427

2ndstr: you're reading it right. That's an excellent summary of Bavituximab mechanism of action.