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biopharm

05/24/13 11:30 PM

#124173 RE: sulaco #124172

Good post Sulaco! eom
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EYEBUYSTOX

05/24/13 11:41 PM

#124174 RE: sulaco #124172

No rush. Thanks for the help. Yes. You cyber intellectually body-slammed the poor fella. Well played, sir.
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medicaz

05/24/13 11:50 PM

#124175 RE: sulaco #124172

well said/presented sulaco eom
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ImaPseudonym

05/25/13 7:19 AM

#124179 RE: sulaco #124172

It might be important to distinguish between 2 issues:

Does hypoxia (further) promote tumor growth? It looks like the answer to this has been commonly thought to be 'yes', but that that may be wrong and/or too simplistic. This seems to me to be what the passages you quote are talking about.

Is hypoxia more prevalent in larger/more progressed tumors than in smaller ones? This is what is at issue with vin..'s bavi bashing.

An interesting read (at least to my untrained eye) is this:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2460565/

Which describes hypoxia in very small <1mm tumors and speculates about the relevance of micrometasteses to overall survival. Maybe this is where bavi is able to make a difference.

And, I suggest with equal qualifications: Mr. Whistler, perhaps that portrait of your mother would make her look better if she were holding a cute furry kitten and smiling.