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iwfal

05/03/13 1:14 PM

#160721 RE: poorgradstudent #160720

ARQL -

Right, and the antibodies they used for the immunoprecipitations were polyclonal, so they would not be meaningfully effected by point mutations in the protein.



Ok - didn't catch that. Thanks. But note that in my first post on this subject I actually pointed to a constitutively activated Met that was not just a "point mutation" since it was a conjoining of a part of Met and a part of some other gene. That said I have no idea what percentage of constitutively activated Met is much more than just a point mutation.

And thanks again for the consult and push back.