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genisi

05/03/13 2:42 PM

#160724 RE: DewDiligence #160666

Are you also significantly less optimistic about AGN's dual-acting (VEGF/PDGF) DARPin in preclinical development? According to yesterday's CC, the plans and timeline for this drug haven't changed at all, but this assertion might include a modicum of spin.

Of course I'll be more confidant when I see DARPin's phase IIb data, but I don't think safety was the issue, and as for efficacy the dual DARPin has theoretically a better shot to begin with, so for now I'm not less optimistic about it.