There is an Israeli vaccine company named Biondvax that is in pursuit of a Universal Flu Vaccine. It only increase protection 10% in elderly and they acted like this was a major accomplishment.
From 2/2012
(TASE: BNDX) today announced positive results from its second Phase II clinical trial (BVX-005) of the Universal Influenza Vaccine (Multimeric-001) developed by Biondvax for improving existing flu vaccines in elderly. The vaccine was found to be safe and well tolerated, and induced robust cellular and humoral immune responses in elderly patients (65+), successfully meeting the primary safety and secondary immunogenicity endpoints. In addition, when given as a primer before boosting with a commercially available seasonal influenza vaccine (trivalent inactivated vaccine, or TIV), Multimeric-001 vaccine enhanced the performance of the TIV by increasing immunity to influenza strains contained in the TIV ("prime-boost" regimen). The Multimeric-001 vaccine improved immunity to influenza in the elderly without the need for any adjuvant. The effectiveness of priming with Multimeric-001 was determined by means of hemagglutination inhibition (HAI) assays. HAI-based immune measures are utilized by US and European regulatory authorities to approve and license existing influenza vaccines.
We are excited to report that this prime-boost indication for our universal flu vaccine increased immunity to TIV flu strains by more than 10 % - that could translate into over 35 million extra elderly people that potentially avoid the slippery slope of flu illness leading to flu complications, hospitalization and death in this age group."