What unmet need is that?
Sorry, but unless 113 shows it head in egfr, I don't see it. 113 would be a me too in Alk + (although a potentialy better me too). I don't know enough about breakthrough status to opine if 113 would qualify for it w/o filing an unmet need (ie egfr).
This, along with Harv's sales, is a modestly bearish development to the simpleton crowd in the short term as I see it.