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oc631

02/05/13 12:25 AM

#156453 RE: oc631 #156451

One more thought on the GILD C.C.



The suggestion that longer 24-week dosing might improve Sofo/Riba GT3 SVR rates is non-sense. The difference between interferon-based and oral therapy is becoming quite clear. Whereas 24-weeks of interferon-based dosing brought exceedingly higher SVR rates this is not the case going beyond 12-weeks of oral treatment.


This is nothing more than false hope being fed to analysts.
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genisi

02/05/13 10:58 AM

#156461 RE: oc631 #156451

The Sofosbuvir/Daclatasvir oral combo demonstrated 100% SVR24 rates in GT2/GT3 patients (Phase 2 / n=14).

Note that in that phase II of sofosbuvir + daclatasvir w/wo ribavirin treatment duration was 24 weeks in GT2/3 and perhaps there were other differences like cirrhotic patients.